Pharm 2 abx Exam Questions and Answers 100% Verified
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Pharm 2 abx
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Pharm 2 Abx
What is the treatment of choice for otitis media? What if sxs persist after starting the
treatment? - ️️DOC: amoxicillin / amoxicillin+clavulanate
Continue this tx, even if sxs persist
What are the ABX tx for an uncomplicated UTI? - ️️Bactrim, Focfomycin, or
Nitrfurantoin
What are the ...
Pharm 2 abx Exam
What is the treatment of choice for otitis media? What if sxs persist after starting the
treatment? - ✔️✔️DOC: amoxicillin / amoxicillin+clavulanate
Continue this tx, even if sxs persist
What are the ABX tx for an uncomplicated UTI? - ✔️✔️Bactrim, Focfomycin, or
Nitrfurantoin
What are the ONLY G+ bacteria that likely cause a complicated UTI? -
✔️✔️S.saprophyticus, S.aureus, Enterococcus
What is special about Fosfomycin? - ✔️✔️It is a 1 dose/1 time only drug for tx of UTI
What infections is doxycycline used for? - ✔️✔️Works well to treat S.aureas -esp
MRSA. It is bacterioCIDAL - so, preferred over Linezolid - and is offered PO (so, good
for outpatient)
Ex: prurulent cellulitis and diabetic foot ulcers
What are some ABX options to treat MRSA? - ✔️✔️Bactrim, doxycycline, linezolid,
clindamycin, and Vanco
What antibiotics work by binding to the 30s subunit of a bacterium's Ribosome? -
✔️✔️Tetracyclines: doxycycline, minocycline, tetracycline
Tigecycline
A pt presents w/urinary frequency, urgency, flank pain, and low grade fever. What is the
BEST abx treatment? - ✔️✔️Tx - cipro/Levo or Bactrim
An expectant mother presents with urinary frequency, urgency, and flank pain. What are
the abx options? - ✔️✔️Amoxicillin-clavulanate
Cephalexin
Nitrofurantoin
What ABX should you AVOID in tx of acute pyelonephritis in pregnant women? -
✔️✔️AVOID: Bactrim, fluoroquinolones, and tetracyclines
What are the side effects to Bactrim? - ✔️✔️Crystaluria, QT prolongation, interstitial
nephritis, and allergic reactions
A patient w/ESRD presents with a UTI. What abx is a good option for treatment? What
abx should you avoid? - ✔️✔️Alternative: Ceftriaxone @ 2g (instead of the usual 1g)
, Avoid: nitrofurantoin
** renally adjust the dose of amoxicillin **
Of the "complicated" UTI abx options, which ones treat Gram Neg bacteria? -
✔️✔️Ceftriaxone
Cephalexin
Nitrofurantoin
A 67yo M pt presents w/fever, chills, frequency, urgency, and flank pain. What are the
best abx options? - ✔️✔️Vanco and Ceftriaxone (always treat like a complicated UTI)
What are good abx options for a pseudomonas CNS infection? - ✔️✔️Cefepime
Ceftolazine + tazo
Meropenam
Aztreonam
Ciprofloxacin
What is the dosing paradigm re: CNS infections? - ✔️✔️It is the inflammatory process
related to CNS infections that allows high doses of ABX to cross the BBB. As the
inflammation is reduced, it is more difficult for the ABX to cross the BBB
What is different about the treatment for a pt >60yo w/CNS infection (vs a younger pt)?
Why do we add this medication? - ✔️✔️You add ampicillin to the Ceftriaxone (or
Ceftazadime) and Vanco. Ampicillin is there for LIsteria coverage
Re: CNS infections, what is the additional concern for immune compromised pts? What
do we add to their regimen? - ✔️✔️Pseudomonas - so add Cefepime or Ceftolozane +
tazobactim (alternatives: meropene, aztreonam, ciprofloxacin)
In general, ABX that cover Pseudemonas are: - ✔️✔️Pippa - pipercillin/tazo
Called - cefapime
CeCe - ceftazadime
Az - aztreonam
Toby. - tobramycin
Gently. - gentamycin
Amikated. - amikacin
Mery Cipro's. - meropenam, ciprofloxacin
Leg. - levofloxacin
What is the caution with the use of Foscarnet to treat CNS infections? - ✔️✔️It is an
alternative to acyclovir (treats viral infections) - it may cause kidney damage - so careful
w/pts w/renal diz
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