©THEBRIGHT EXAM SOLUTIONS
11/9/2024 2:18 PM
Pharmacology 5334 Final Exam Questions
And Answers 100% Pass
PCN drug-drug interactions - answer✔-aminoglycosides
-bacteriostatic antibiotics
-probenecid
Treatment for ONYCHOMYCOSIS - answer✔Terbinafine (Lamisil) 1 tab daily x 3-6 months po
Best treatment for chlamydia - answer✔Aziythromycin 1gm 1x dose
or
Doxycycline 100 mg po twice a day for 7 days
Patient with vaginal candidiasis, what is the treatment? - answer✔Fluconazole 150mg po once
Treatment for uncomplicated cervical gonorrhea - answer✔Ceftriaxone, 250 mg IM once, plus
azithromycin, 1 g PO once
Patient with tinea capitis, what is the TX? - answer✔Very difficult to treat topically
Griseofulium po 6-8 weeks
or
Terbinafine (Lamisil) po 2-4 weeks
Narrow Spectrum PCN - answer✔PCN G (procaine), PCN G (benzathine), PCN V
Bugs they fight: GRAM(+) cocci- 1st drug of choice against Strep (pneumonia, pharyngitis, endocarditis) ,
Clostridium (tetanus, anthrax, gas gangrene)Neisseria, spirochete (syphilis)
Lauren comes into the clinic and is diagnosed with Trichomoniasis. The NP can prescribe: -
answer✔Metronidazole, 2 g PO once or
Tinidazole, 2 g PO once
Penicillinase-resistant PCN - answer✔Oxacillin, Nafacillin, Dicloxacillin
, ©THEBRIGHT EXAM SOLUTIONS
11/9/2024 2:18 PM
Bugs they fight: Staph
Broad spectrum PCN - answer✔Ampicillin- ampiciliin/sulbactam (Unasyn)
Amoxicillin- amoxicillin/ER (Moxatog), Amoxicillin/Clavulanate(Augmentin)
Bugs they fight: Good against GRAM (-)H. influenza, e-coli, proteus mirabilis, enterococci, salmonella and
shigella
Extended Spectrum PCNs - answer✔Piperacillin/tazobactam (Zosyn)
Bugs they fight: same as broad spectrum + pseudomonas, klebsiella, bacterial fragilis
Beta-lactamase inhibitors - answer✔clavulanic acid, sulbactam, tazobactam
**Can not be given on their own, only in combo with PCN's i.e.> Augmentin, Unasyn, Zoysn
Cephalosporin Generation 1 - answer✔-cephalexin
-cephazolin
-cephadoxil
**Cephlasporinase will destroy**
Not the drug of choice for active infections- good for prophylaxis prior to sx
Cephlasporin (2nd generation) - answer✔Cefuroxime-most common
Bugs they fight: h.influenza (pneumonia), otitis sinusitis, res. tract infection
Cephlasporin (3rd generation) - answer✔Cefotaxime, Cefdinir, Cefixime, Cefodoxime, Ceftaazidime,
Ceftibuten, Ceftriaxone
**Can penetrate CSF fluid**
Bugs they fight: Great against GRAM (-) bacteria causing meningitis, h.influenza, klebsiella, proteus,
salmonella
Cephlasporin (4th generation) - answer✔Cefepime-hospital associated pneumonia's &
Ceftolozone/tozobactam (Zerbaxa)- complicated UTI's and intraabdominal infections
Cephlasporin (5th generation) - answer✔Ceftaroline (Teflaro)-MRSA
Cephalosporin and PCN - answer✔Cross allergy w/PCN
Carbapenems - answer✔Only 4: Imipenem, Meropenem, Ertrapenem, Doripenem
EXTREMELY broad spectrum, **only given IV**
not active against MRSA
