Pharm 553 Unit 5 Exam|30 Answered
Questions
Elderly patients who are started on levothyroxine for thyroid replacement
should be monitored for: - -Excessive sedation
******Tachycardia and angina
Weight gain
Cold intolerance
- Potentially fatal granulocytopenia has been associated with treatment of
hyperthyroidism with propylthiouracil. Patients should be taught to report: -
-Tinnitus and decreased salivation
******Fever and sore throat
Hypocalcemia and osteoporosis
Laryngeal edema and difficulty swallowing
- Metformin is a primary choice of drug to treat hyperglycemia in type 2
diabetes because it: - -Substitutes for insulin usually secreted by the
pancreas
******Decreases glycogenolysis by the liver
Increases the release of insulin from beta cells
Decreases peripheral glucose utilization
- Hypoglycemia can result from the action of either insulin or an oral
hypoglycemic. Signs and symptoms of hypoglycemia include: - -"Fruity"
breath odor and rapid respiration
Diarrhea, abdominal pain, weight loss, and hypertension
******Dizziness, confusion, diaphoresis, and tachycardia
Easy bruising, palpitations, cardiac dysrhythmias, and coma
- Sulfonylureas may be added to a treatment regimen for type 2 diabetics
when lifestyle modifications and metformin are insufficient to achieve target
, glucose levels. Sulfonylureas have been moved to Step 2 therapy because
they: - -Increase endogenous insulin secretion
******Have a significant risk for hypoglycemia
Address the insulin resistance found in type 2 diabetics
Improve insulin binding to receptors
- Treatment with insulin for type 1 diabetics: - -******Starts with a total daily
dose of 0.2 to 0.4 units per kg of body weight
Divides the total doses into three injections based on meal size
Uses a total daily dose of insulin glargine given once daily with no other
insulin required
Is based on the level of blood glucose
- The American Heart Association states that people with diabetes have a 2-
to 4-fold increase in the risk of dying from cardiovascular disease.
Treatments and targets that do not appear to decrease risk for micro- and
macro-vascular complications include: - -******Glycemic targets between 7%
and 7.5%
Use of insulin in type 2 diabetics
Control of hypertension and hyperlipidemia
Stopping smoking
- Drugs used to treat diabetic peripheral neuropathy include: - -
Metoclopramide
Cholinergic agonists
Cardioselective beta blockers
******Gabapentin
- The goals of therapy when prescribing hormone replacement therapy
(HRT) include reducing: - -Cardiovascular risk
Risk of stroke or other thromboembolic event
Breast cancer
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