UT TYLER PHARM FINAL (TESTS 1-3) QUESTIONS
WITH 100% CORRECT ANSWERS
Pharmakinetics - CORRECT ANSWER-process of drug movement to achieve drug action;
absorption, distribution, metabolism (biotransformation), and excretion
Absorption - CORRECT ANSWER-movement of drug particles from GI tract to body fluids;
passive or active
Passive Absorption - CORRECT ANSWER-diffusion; movement from high to low concentration;
energy not required
Active Absorption - CORRECT ANSWER-carrier such as enzyme or protein used to move drug
against a concentration gradient
Pinocytosis - CORRECT ANSWER-process by which cells carry a drug across their membrane by
engulfing drug particles
Bioavailability - CORRECT ANSWER-percentage of administered drug dose that reaches the
systemic circulation; after absorption and first-pass metabolism
Affected by:
1) drug form 2) route of admin 3) GI mucosa and motility 4) food and other drugs 5) changes in
liver metabilism or inadequate hepatic flow
Distribution - CORRECT ANSWER-process by which the drug becomes available to body fluids
and body tissues
Affected by:
UT TYLER PHARM FINAL (TESTS 1-3) QUESTIONS
WITH 100% CORRECT ANSWERS
,1) blood flow 2) drug's affinity to tissue 3) protein binding effect
Protein Binding - CORRECT ANSWER-portion of drug that is bound is inactive b/c it is
unavailable to receptors; portion that remains unbound is free, active drug (only free drugs
cause pharmacologic response)
Metabolism - CORRECT ANSWER-process by which body inactivates or biotransforms drugs;
liver is primary site
Half-Life - CORRECT ANSWER-time it takes for one half of drug concentratio to be emliminated
Additive Effect - CORRECT ANSWER-when two drugs of similar action are administered; sum of
the effects of two drugs
Synergistic Effect - CORRECT ANSWER-when two or more drugs are given together, one drug
can potentiate the other; clinical effect is substantially greater than the combined effect of the
two
Antagonist Effect - CORRECT ANSWER-when two drugs have opposite effects; each drug cancels
out the effect of the other
Drug-Food Interaction - CORRECT ANSWER-may increase, decrease, or delay drug absorption
Ethical principles related to med admin - CORRECT ANSWER-respect to persons, beneficence,
justice, and veracity
UT TYLER PHARM FINAL (TESTS 1-3) QUESTIONS
WITH 100% CORRECT ANSWERS
, Autonomy - CORRECT ANSWER-right to self determination; patient can refuse any and all
treatments
Beneficence - CORRECT ANSWER-duty to do good and not harm to others; to maximize benefits
and minimize possible harm that right that might occur in research
Justice - CORRECT ANSWER-requires all people to be treated fairly; equal access to health care;
limited when it interferes with the rights of others
Veracity - CORRECT ANSWER-requires health care personnel to tell the whole truth; patient has
right to hear bad news
Nursing Process - CORRECT ANSWER-patient centered collaborative care; each phase
dependant on preceding phase; includes assessment, nursing diagnosis, planning,
implementation, and evalutation
Assessment - CORRECT ANSWER-characterized by systemic validation and documentation of
information; made throughout nursing process; includes subjective and objective date
Nursing Diagnosis - CORRECT ANSWER-based on analysis of assessment data; fascilitates
development of an individualized care plan for each patient
Planning - CORRECT ANSWER-characterized by goal setting or expected outcomes; patient
centered
Implementation - CORRECT ANSWER-education, medication administration, patient care, and
other interventions
Evaluation - CORRECT ANSWER-nurse determines how well goals are obtained
UT TYLER PHARM FINAL (TESTS 1-3) QUESTIONS
WITH 100% CORRECT ANSWERS
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