Lecture 23: Blood and its Functions
Describe the seven functions of blood
o Exchanging gases
o Distribution of solutes
o Immune functions
o Maintain body temperature
o Seal wounded blood vessels via blood clots
o Maintaining acid-base homeostasis
o Stabilizing blood pressure
Describe the components of blood
o Plasma
Makes up 55% of blood volume
Contains
Water
o Primary component of plasma 90%
o Amount will determine blood viscosity
Less water blood becomes more viscous
Proteins
o Make up 9% of plasma volume
o Proteins made mostly by liver
o Will not dissolve in water due to size forms colloid
mixture
o Important plasma proteins
Albumin
Large protein made by liver
Function
o Responsible for blood’s colloid
osmotic pressure
Pressure draws water into
blood via osmosis
Immune proteins
Antibodies
o Produced by leukocytes
Transport proteins
Are hydrophilic
Help move lipid-based compounds
Lipoproteins and beta-globulins are
examples
1
, Clotting proteins
Help form blood clot along with platelets
to stop bleeding from wounded blood
vessels
Solutes
o Make up ~1% of plasma volume
o Will dissolve in water found in plasma to make a
solution
o Examples of solutes found in plasma
Glucose
Amino acids
Nitrogenous wastes
Ions
Small amounts of oxygen and carbon dioxide
Describe the disease cirrhosis
Also known as liver disease
Caused by
o Cancer
o Alcoholism
o Viral hepatitis
Consequence of cirrhosis
o Decrease in production of plasma proteins
Albumin
Decrease results in reduced blood
osmotic pressure
o Blood will lose water to
extracellular spaces and swelling
will ensue
Clotting proteins
Decrease will result in easy bruising and
delays in blood clotting
o Erythrocytes (Red Blood Cells RBCs)
One of the three formed elements in blood (leukocytes [white blood
cells- WBCs] and platelets are the others - described below)
Makes up 44% of total blood volume also known as the hematocrit
Males tend to have a higher hematocrit (40-50%) than females
(36%-44%)
Life span of a RBC is ~100-120 days
o RBCs do not have cellular machinery to make new cells
or repair damage that occurs to RBCs
Describe the structure of RBCs
Biconcave disc
2
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