NAPLEX EXAM QUESTIONS AND CORRECT
ANSWERS GRADED A+|| LATEST 2024-2025
A young adult female patient was prescribed an appropriate dose of Tylenol #3 during an
emergency department visit. Within 48 hours, the patient was brought back to the emergency
department by ambulance due to respiratory depression and somnolence. Which of the following
is the most likely cause of this response?
Answer
A. The patient is HLA-B*5701 positive.
B. The patient has 2C192 or 3 alleles.
C. The patient is a 2D6 ultra-rapid metabolizer.
D. The patient has a deficiency of thiopurine methyltransferase (TPMT).
E. The patient has 2C92 or 3 alleles. - ANSWER: C
The patient is a 2D6 ultra-rapid metabolizer.
A pharmacist will counsel a female patient who is beginning lamotrigine therapy for bipolar
disorder. There are no interacting medications on the profile. Which of the following counseling
statements should the pharmacist share with the patient? (Select ALL that apply.)
Answer
A. This medication can cause serious skin reactions, including a very severe rash.
B. It is important that this medication is titrated slowly; follow the instructions carefully.
C. One of the brand names for this medication is Trileptal.
D. Your starter kit packaging should be orange.
E. Your starter kit packaging should be blue. - ANSWER: A
This medication can cause serious skin reactions, including a very severe rash.
B. It is important that this medication is titrated slowly; follow the instructions carefully.
, D. Your starter kit packaging should be orange.
By Day #2 of her visit, DB's oxygen saturation has gradually improved and her physician has
asked the pharmacist to convert her SoluMedrol to an equivalent dose of oral prednisone. What
is the equivalent daily dose of oral prednisone in milligrams? (Answer must be numeric; no units
or commas; round the final answer to the nearest WHOLE number.)
Solumedrol IV 20mg q8h - ANSWER: 75 mg prednisone daily
Which of the following statements concerning sumatriptan is correct?
Answer
A. It is contraindicated in patients with uncontrolled hypertension.
B. It is available as a needle-free intramuscular injection.
C. Popular brand names include Maxalt and Zomig.
D. It is a serotonin antagonist that causes vasodilation of cranial blood vessels.
E. The nasal spray formulation must be primed before use. - ANSWER: A
It is contraindicated in patients with uncontrolled hypertension.
Which which vitamin deficiency is at risk with excessive alcohol use?
A. Vitamin B1 (thiamine)
B. Vitamin B2 (riboflavin)
C. Vitamin B3 (niacin)
D. Vitamin B6 (pyridoxine)
E. Vitamin B12 (cobalamin) - ANSWER: A
Vitamin B1 (thiamine)
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