,1. Which of the following pathophysiological processes is directly
associated with congestive heart failure?
- A) Decrease in preload
- B) Increase in cardiac output
- C) Myocardial hypertrophy
- D) Decrease in afterload
- Answer: C) Myocardial hypertrophy
- Rationale: Myocardial hypertrophy occurs as the heart muscle
thickens in response to increased workload to maintain cardiac
output, which is associated with congestive heart failure.
, 3. In Type 1 Diabetes Mellitus, which autoimmune mechanism
primarily destroys pancreatic β-cells?
- A) T-cell mediated cytotoxicity
- B) B-cell antibody production
- C) Natural killer cell activation
- D) Complement activation
- Answer: A) T-cell mediated cytotoxicity
- Rationale: In Type 1 Diabetes Mellitus, autoreactive T-cells
mediate the destruction of insulin-producing pancreatic β-cells.
4. Which pathophysiological mechanism is the primary cause of
edema in nephrotic syndrome?
- A) Increased capillary permeability
- B) Decreased plasma oncotic pressure
- C) Increased hydrostatic pressure
- D) Lymphatic obstruction
- Answer: B) Decreased plasma oncotic pressure
- Rationale: Nephrotic syndrome leads to severe proteinuria,
reducing plasma protein levels and oncotic pressure, resulting in
edema.
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