How do we classify microbes? - Answer-Prokaryotes: bacteria and arches
Eukaryotes: fungi, protozoa, and algae
Florence Nightingale - Answer-founder of medical statistics
which played a major role in disease in warfare and overcrowded areas
Robert Koch - Answer-founder of the scientific method of microbiology
demonstrated an important aspect of epidemiology - chain of infection
Know Koch's postulates - Answer-1) microbe is found in all cases of the disease, but
absent from healthy individuals
2) microbe is isolated from host and grown in pure culture
3) when microbe introduced into healthy host, the same disease occurs
4) same strain of microbe is obtained from newly diseased host
Alexander Fleming - Answer-discovered the first antibiotic from Penicillium notatum
Aseptic technique - Answer-keeping a sterile environment
not contaminating yourself or others
Antiseptic agents - Answer-chemicals that kills microbes
Watson and Crick - Answer-discovered the double helix
Rosalind Franklin - Answer-helped Watson and Crick in discovering the double helix but
was not recognized
Frederick Sanger - Answer-discovered DNA sequence
, Microbiota - Answer-collection of bacteria, arches and eukaryotic microbes that call us
home
Mutualism - Answer-most of these microbes in and on our bodies give benefits to us
and we give them some benefits
Adhesions - Answer-helps microbes to attach to and colonize epithelial lining
membranes
Colonizations - Answer-the ability of a microbe to affix to a body surface and multiply
Pathogen - Answer-any bacterium virus, fungus, protozoan or worm that cause disease
bacteria, virus, fungal, agents of disease
Pathogenicity - Answer-the ability of that organism to cause disease
Parasites - Answer-disease causing protozoa and worms
Primary pathogens - Answer-disease causing microbes with means to branch healthy
immune system
Opportunistic pathogens - Answer-cause of disease only in a compromised host
Virulence - Answer-degree or severity of disease
LD50 - Answer-lethal dose
what it takes to kill off 50% of a population
ID50 - Answer-infectious dose
what it takes to infect 50% of a population
Invasion - Answer-ability of some pathogens to actually enter and live inside cells of a
human or non-human animal host
Invasiveness - Answer-the ability of a bacterial pathogen to rapidly spread through
tissue
Fundamental host-pathogens interactions - Answer-1) Attachment
2) Immune avoidance
3) obtaining nutrients from host
Signs vs. Symptoms - Answer-Sign: something you can see
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