ACTIVE LEARNING TEMPLATE: Medication
Maryann Akwensivie
STUDENT NAME _____________________________________
Zoloft
MEDICATION __________________________________________________________________________ 3
REVIEW MODULE CHAPTER ___________
Selective Serotonin Reuptake inhibitors (SSRIs)
CATEGORY CLASS ______________________________________________________________________
PURPOSE OF MEDICATION
Expected Pharmacological Action Therapeutic Use
Inhibits neuronal uptake of serotonin in the Antidepressant action, Decreased incidence of panic attacks.
Decreased obsessive and compulsive behavior.Decreased feelings
Central Nervous System, thus potentiating of intense fear, helplessness, or horror. Decreased social anxiety.
the activity of serotonin. Has little effect on Decrease in premenstrual dysphoria.
norepinephrine or dopamine.
Complications Medication Administration
Increase sweating, hot flashes, rash, pharyngitis, rhinitis, tinnitus, visual Depression/OCD
abnormalities, diabete, hyponatremia, PO (Adults): 50 mg once daily in the morning or evening
initially; after several wk may be ↑ at weekly intervals up to
diarrhea, dry mouth, nausea, abdominal pain, altered taste, anorexia, 200 mg/day, depending on response.
constipation, dyspepsia, flatulence, appetite, vomiting, sexual dysfunction,
menstrual disorders, urinary disorders, urinary frequency, back pain, myalgia Panic Disorder
PO (Adults): 25 mg once daily initially, may ↑ after 1 wk to
50 mg once daily.
PTSD
PO (Adults): 25 mg once daily for 7 days, then ↑ to 50 mg
once daily; may then be ↑ if needed at intervals of at least
7 days (range 50–200 mg once daily).
Contraindications/Precautions
Contraindicated in: Hypersensitivity, Concurrent use of pimozide; Oral
concentrate contains alcohol, avoid in patients with known intolerance.
Nursing Interventions
Use Cautiously:Severe hepatic or renal impairment, Patients with a
history of mania, History of suicide attempt, Angle-closure glaucoma Do not confuse sertraline with cetirizine or Soriatane
(acitretin). Periodically reassess dose and continued need
for therapy. Administer as a single dose in the morning or
evening. For oral concentrate, use dropper provided to
remove oral concentrate and mix with 4 oz (1/2 cup) of
water, ginger ale, lemon/lime soda, lemonade or orange
juice. Do not mix in advance. May cause drowsiness or
dizziness. Caution patient to avoid driving and other
Interactions activities requiring alertness until response to the drug is
known.
Concurrent use with alcohol is not recommended.
May increase levels/effects of warfarin, phenytoin, tricyclic
antidepressants, some benzodiazepines (alprazolam), cloazapine,
or tolbutamide. Increase risk of bleeding with NSAIDS, aspirin,
clopidogrel, or warfarin.
Client Education
Advise patient to wear sunscreen and protective clothing to
prevent photosensitivity reactions.
Advise patient to notify health care professional if headache,
Evaluation of Medication Effectiveness weakness, nausea, anorexia, anxiety, or insomnia persists.
Advise patient, family, and caregivers to look for suicidality,
especially during early therapy or dose changes. Notify
Decrease in obsessive-compulsive behaviors. health care professional immediately if thoughts about
suicide or dying, attempts to commit suicide; new or worse
Decrease in frequency and severity of panic attacks. depression or anxiety; agitation or restlessness; panic
attacks; insomnia; new or worse irritability, aggressiveness,
Decrease in symptoms of PTSD. acting on dangerous impulses, mania, or other changes in
Decrease in social anxiety disorder. mood or behavior or if symptoms of serotonin syndrome
occur.
Decrease in symptoms of premenstrual dysphoric disorder.
ACTIVE LEARNING TEMPLATES