NUR 635 Advanced Pharmacology Midterm Exam
Review 2024/2025 with 100% correct Solutions
- ✔✔baclofen
atomoxetine(Straterra), clonidine, and guanfacine are used in tx of which DO? - ✔✔ADHD
initial intervention for infrequent migraine HA - ✔✔HA diary
Meds that may cause QT prolongation - ✔✔methadone, tricyclic antidepressants, amiodarone
CI for a triptan includes - ✔✔htn, CAD, MAOI use. Triptans used to ease migraine symptoms
by calming overactive nerves in the brain and vasoconstriction of blood vessels in the brain
What to give for hives and wheezing r/t pb? - ✔✔epinephrine IM
Beta blockers have been used to treat _____________, _________, ____________ - ✔✔post
MI, HTN, HF
Drug route for 100% bioavailability - ✔✔IV
Chronic renal failure will affect ___________ element of pharmacokinetics - ✔✔excretion
Adrenergic antagonists or alpha blockers cause ____________________ - ✔✔vasodilation
,in addition to lowering BP, alpha blockers are used in tx of ________ - ✔✔BPH
symptoms of BPH - ✔✔urinary frequency and urgency, nocturia, hesitancy and difficulty
continuing to urinate, reduced force and size of urinary stream ("weak" stream), sensation
of incomplete bladder emptying, straining to begin urination, post-void dribbling or leaking,
hematuria, enlarged prostate
Common side effect of ACE inhibitors - ✔✔dry cough
Angina is a pain caused by _________________ - ✔✔cardiac ischemia
All pts with angina should receive what drug for prophylaxis of a myocardial infarction? -
✔✔aspirin- antiplatelet
lifestyle modifications to reduce cardiac risk include - ✔✔Wt loss (at least 10lbs), stop
smoking, daily exercise
Pt w/ heart failure, angina w/walking and slight limitation of activity is what class? - ✔✔Class II
pt is taking hydrochlorothiazide(HCTZ) for HTN. What lab is most impt to monitor? - ✔✔K, for
hypokalemia.
Hypokalemia can result in abnormal heart rhythms, cramp and twitch muscles.
HCTZ, thiazide diuretic, removes excess salt and water
cardiac remodeling in HF - ✔✔Worsens HF. The wall of the left ventricle thickens and
enlarges in an attempt to compensate for the increased workload.
, class of medication in pts post MI to prevent cardiac remodeling - ✔✔ACE inhibitors. ACE
inhibitors are known to increase tissue bradykinin accumulation. Bradykinin has antigrowth
effects and reduces vasomotor tone.
When tx hyperlipidemia, calculation ____________ risk will help to determine tx. - ✔✔ASCVD
risk, Atherosclerotic cardiovascular disease
Class of medication contraindicated in pts w/liver failure - ✔✔HMG-CoA
inhibitors(Statins). Because all statins are hepatically cleared and can cause elevations in
liver biochemistries, there is a concern that patients with underlying liver disease may be
at increased risk for hepatotoxicity.
Which anticoagulant has the quickest onset of action? - ✔✔Heparin
Pts receiving heparin are at risk for what adverse rxn? - ✔✔thrombocytpenia. Condition in
which you have a low blood platelet count, not enough platelets, increased risk of bleeding
Why would heparin and warfarin be given at the same time? - ✔✔warfarin has a delayed effect
Risk factors that increase a pts ability to bleed - ✔✔herbal supplements, aspirin use, TPA
Factor Xa levels may be monitored in pts on this med - ✔✔low molecular wt heparin,
LMWH has better bioavail and longer half-life than heparin(ex: enoxaparin)
Meds to be avoided in pregnancy - ✔✔statins, warfarin, ACE inhibitors
Post hip replacement, med used to prevent DVT - ✔✔enoxaparin
Pt started on warfarin for a fib should be taught that________ - ✔✔INR should be between 2-3
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