T/F: in both developed and developing countries, rotavirus is the most common
GI viruses
true
what structure of GI viruses prevents degradation
capsid
which GI virus has the strongest capsid
rotavirus
what per cent of infectious diarrhoea is caused by viruses
75-90%
how many deaths are caused by gastroenteritis/infectious diarrhoea
1.3 million deaths
what groups are most affected by gastroenteritis/infectious diarrhoea
children < 5 and developing world
what is viral gastroenteritis
inflammation of the epithelial lining of the stomach or small intestine
what are symptoms of viral gastroenteritis
watery diarrhea, vomiting, fever, chills, abdominal pain
what is main complication of viral gastroenteritis
dehydration
how is viral gastroenteritis transmitted
person to person - fecal oral route (contaminated food/water, objects, surfaces,
airborne particles)
what are four viruses that cause viral gastroenteritis
, norovirus, rotavirus, astrovirus, adenovirus
how is viral gastroenteritis diagnosed
typically only based on symptoms but can do stool testing in outbreaks or
prolonged symptoms
how is viral gastroenteritis generally treated
symptomatic care
how can viral gastroenteritis be prevented
hand washing, decontamination of surfaces, rotavirus vaccine for kids
glucose facilitates absorption of sodium (and water) on a ___:____ molar basis
1:1
what two electrolytes to replete losses during diarrhea and vomiting
sodium and potassium
what buffer corrects acidosis resulting from severe diarrhea and vomiting
citrate
what is total osmolarity of WHO oral rehydration
245 mmol/L
what is contained in WHO oral rehydration solution
sodium, chloride, glucose, potassium, citrate
T/F: the WHO ORS formula has caused mortality in children with acute
diarrhea to fall from 5 million to 1.3 million deaths per year
true
what family is rotavirus in
Reoviridae
rotavirus is round, _________ (enveloped or non-enveloped), and _______
(RNA/DNA)
non-enveloped, dsRNA
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