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PSYCHOPHARMACOLOGY WILKES N552
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PSYCHOPHARMACOLOGY WILKES N552
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PSYCHOPHARMACOLOGY WILKESN552
Dissociation6-6ans--
defense6mechanism6that6protects6a6person6from6overwhelming6anxiety6by6emotionally6s
eparating
Depersonalization6-6ans--
unreality6or6detachment6from6one's6body,6thoughts,6feeling6and6actions
Derealization:6-6ans--unreality6or6detachment6from6one's6surroundings
Body6dysmorphic6disorder6-6ans--
Preoccupation6with6one6or6more6perceived6defects6or6flaws6in6physical6appearance6
Spends6significant6time6trying6to6correct6perceived6flaw6with6makeup,6dermatological6pro
cedures6or6plastic6surgery
6 Txt:6SSRI6and6or6CBT
Hoarding6disorder6-6ans--
Persistent6difficulty6discarding6possessions6regardless6of6actual6value6
Results6in6accumulation6of6possessions6that6compromise6living6space6or6inability6to6funct
ion6
Patients6who6remain6resistant6to6psychosocial6interventions,6or6who6lack6access6to6them
,6can6be6provided6a6trial6of6a6serotonin-
reuptake6inhibitor,6particularly6if6they6have6a6comorbid6affective6or6anxiety6disorder;
Trichotillomania6-6ans--
Recurrent6pulling6out6one's6hair6despite6repeated6attempts6to6stop.6
Txt:6SSRI,6Clomipramine;6atypical6antipsychotics,6lithium
Excoriation6Disorder6-6ans--
Recurrent6skin6picking6that6results6in6lesions6despite6attempts6to6stop.6
Cognitive-
behavioral6therapies6may6be6beneficial6for6patients6accepting6psychiatric6referral
, 6 Txt:6SSRIS,6antipsychotics,6anxiolytics
Posttraumatic6Stress6Disorder6(PTSD)6-6ans--Re-
experiencing6of6an6extremely6traumatic6event6accompanied6by6symptoms6of6increased6a
rousal6and6avoidance6of6stimuli6associate6with6the6trauma.
PTSD6treatment6-6ans--1st6line:6SSRIS6(Zoloft,6Celexa)6or6SNRIS6(Venlafaxine)6
FDA6approved6meds:6Sertraline6(Zoloft)6and6Paroxetine6(Paxil)6
Alpha-16agonist6(Prazosin)=6targets6flashbacks;6nightmares6and6hypervigilance6
Psychotherapy6(CBC-6exposure6therapy6etc.)
•6PTSD6-6ans--
is6a6potentially6debilitating6disorder6that6can6occurs6after6a6traumatic6event.6
Commonly6described6in6war6veterans6•6
Can6also6present6in6those6experiencing6non-6war6events
PTSD6-6ans--•6Clinical6syndrome6is6characterized6by646clusters6of6symptoms:6
Re-experiencing6the6trauma6(with6intrusive6thoughts,6nightmares,6or6flashbacks)6•6
Emotional6numbing6•6
Avoidance6behaviors6•6
Persistent6hyperarousal6and6mood6symptoms6(depression,6irritability,6anger)
Difference6between6Acute6Stress6Disorder6and6PTSD:6-6ans--
When6an6individual6experiences6a6traumatic6event6and6displays6anxiety6symptoms6that6l
asts6for6only6a6short6duration,6the6condition6is6opposed6to6PTSD.6
For6the6diagnosed6as6ASD6as6condition6to6be6diagnosed6as6ASD,6symptoms6must6occur6
within6one6month6of6trauma6and6last6for6not6more6than6one6month.6The6symptoms6of6AS
D,6however,6are6similar6to6those6observed6in6PTSD.
Comorbidity6Assessment:6PTSD6-6ans--It6is6important6to6look6for:6
Substance6use6disorders6(avoid6benzodiazepines)6
Depression6
Bipolar6disorder6
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