NURS 5461 DEPRESSION EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED
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Course
NURS 5461
Institution
NURS 5461
NURS 5461 DEPRESSION EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED
Limbic System. amygdala
Gauge and modulate emotions/ thoughts of death and guilt,
Limbic system hippocampus
Affects memory/concentration less size/ neurogenesis in depression
Frontal cortex
Linked to depressed m...
transporters Neurons get exposed to glutamate and can no longer function Progressive
depression Damage to neurons (neurotoxicity) 2x greater risk of dementia with
depression! not enough stabilization with GABA
PFC hyperactivity
↑CRF released from hypothalamus ACTH released from pituitary Glucocorticoids
(cortisol) released from adrenal cortex Excessive glucocorticoid release may cause
hippo-campal atrophy Atrophy leads to chronic activation of HPA axisDepression,
anxiety result. Antidepressants can reverse
Hypothalamic Dysregulation Circadian Rhythms of Sleep
Delayed sleep onset
Shortened REM latency
Increased length of 1st REM period
Abnormal delta sleep
May be reported as lack of sleep or atypical feature
of hypersomnia
Antidepressant meds treat circadian dysregulation
and can restore normal sleep architecture
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