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Pharm 124 - Pharmaceutics Midterm Exam Questions and Answers 100% Pass
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Pharm 124 - Pharmaceutics Midterm Exam Questions and Answers 100% Pass Pharmaceutics - This term covers a wide range of subjects including: physical pharmaceutics, biopharmaceutics, dosage form and design, compounding and manufacturing, pharmaceutical technology and manufacturing. This is the...

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  • November 1, 2024
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  • 2024/2025
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©NINJANERD 2024/2025. YEAR PUBLISHED 2024.
Pharm 124 - Pharmaceutics Midterm

Exam Questions and Answers 100%

Pass


Pharmaceutics - ✔✔This term covers a wide range of subjects including:

physical pharmaceutics, biopharmaceutics, dosage form and design,

compounding and manufacturing, pharmaceutical technology and

manufacturing. This is the art and applied science of dosage form and

design. We are looking at the interface b/w drug and body. Simply this

CONVERTS A DRUG INTO A MEDICINE.

What is a Drug? - ✔✔An chemical substance used in the treatment, cure,

prevention or diagnosis of a disease or used to otherwise enhance physical

or mental well being. It is also said to be the medicinal ingredient, active

ingredinet or the active pharmaceutical ingredient. This is not the same

thing as medicine.

API - ✔✔The active pharmaceutical ingredient.

,©NINJANERD 2024/2025. YEAR PUBLISHED 2024.
Medicine - ✔✔This contains more than just the active ingredient, the drug,

it is transforming this into a form that is acceptable to the patient. This can

include the addition or stabilizers, sweeteners, excipients... This is the form

o the drug that is ready to use and is acceptable to the patient.

What is Dosage Form? What is the purpose of choosing a particular

dosage form? - ✔✔This is the form of the drug that is acceptable to the

patient after the addition of additives to make it work perfectly, this is the

medicine in the form of a tablet, a capsule, a suppository, a drink. Different

dosage forms are required for many different reasons.

The objective of this is to achieve predictable therapeutic response to the

drug in the formulation.

Coated Tablets - ✔✔These are used to protect the drug substances from

the destructive influences of atmospheric oxygen or humidity.

Enteric-Coated - ✔✔This is done to protect the drug substances form the

destructive influence of gastric acid after oral administration. This will keep

it protected and intact until it reaches the colon where it will be released.

Capsules and Flavoured Syrups - ✔✔These are used to conceal the bitter,

salt or offensive taste or odour of a drug substance. This is especially

important when it comes to children.

,©NINJANERD 2024/2025. YEAR PUBLISHED 2024.
Suspensions - ✔✔These are used to provide liquid preparations of

substances that are either insoluble or unstable in the desired vehicle.

Syrups and Solutions - ✔✔These are used to provide clear liquid dosage

forms of substances.

Controlled-Release Tablets - ✔✔These are used to provide rate-controlled

drug action. This can be used to reduce the number of times a drug needs

to be administered.

Ointments, Creams and Transdermal Patches - ✔✔These are used to

provide optimal drug action from topical administration sites.

Suppositories - ✔✔These are used to provide insertion of a drug into one of

the body's orfices.

Injections - ✔✔These are used to provide placement of drugs directly into

the blood stream or body tissue. This direct effect allows for it to have its

effect faster. This is also used for things that cannot be taken orally.

Inhalants and Inhalation Aerosols - ✔✔These are used to provide optimal

drug action through inhalation therapy. This is important for people w/

asthma and things like pulmonary obstructive diseases

List the 3 Important Considerations for Dosage form Design - ✔✔1.

Physiochemical properties of the drug

, ©NINJANERD 2024/2025. YEAR PUBLISHED 2024.
2. Biopharmaceutical considerations

3. Therapeutic considerations.

Physiochemical Properties of a Drug - ✔✔This is taken into consideration

when we consider dosage form design. This includes things like:

-structural properties

-dissolution properties

-stability

ADME - drug Absorption, Distribution, Metabolism and Elimination

Biopharmaceutical Considerations (give 3) - ✔✔This is taken into

consideration when we consider dosage form design. This includes:

-the intended site of action (systemic or topical)

-where the drug is absorbed

-what is the onset of action (immediate, sustained or pulse release)

Therapeutic Considerations - ✔✔This is taken into consideration when we

consider dosage form design. This is the nature of the disease state that is

being treated. This defines the:

-type of dosage form (is systemic or local therapy required for targeted

delivery)

-route(s) of administration

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