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Exam (elaborations)

PHAR 100 Final Exam Questions and Answers 100% Solved | Graded A+

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  • PHAR 100
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  • PHAR 100

PHAR 100 Final Exam Questions and Answers 100% Solved | Graded A+ Path of drug from when it enters to exits the body - 1. Absorption 2. Distribution 3. Metabolism 4. Excretion Absorption - the movement of the drug from the site of administration into the bloodstream Distribution - the movem...

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  • November 1, 2024
  • 22
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • PHAR 100
  • PHAR 100
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NinjaNerd
©NINJANERD 2024/2025. YEAR PUBLISHED 2024.
PHAR 100 Final Exam Questions and

Answers 100% Solved | Graded A+


Path of drug from when it enters to exits the body - ✔✔1. Absorption

2. Distribution

3. Metabolism

4. Excretion

Absorption - ✔✔the movement of the drug from the site of administration

into the bloodstream

Distribution - ✔✔the movement of a drug from the blood to the site of action

and other tissues

Metabolism - ✔✔the conversion of a drug to a different chemical

compound.

Excretion - ✔✔moving of the drug and its metabolites out of the body

Routes of drug administration - ✔✔1. Topical

- On the skin

-Transdermal

-Inhalation

,©NINJANERD 2024/2025. YEAR PUBLISHED 2024.

2. Enteral

-Oral

-Suppository

-Buccal



3.Parenteral

-IV

-IM

-Subcutaneous

Why and how do adverse drug reactions occur? - ✔✔Example: a receptor

is activated in a blood vessel by a drug designed to treat hypertension. The

rector is activated by the ligand that is bound to it, and the blood pressure

is lowered. However, this receptor may located in other areas of the body.

The subsequent activation of this receptor in other areas of the body is an

example of an adverse effect.

Adverse effects - ✔✔1. Extension of therapeutic effect

2. Unrelated to main drug action

3. Allergic reaction

4. Dependence and addiction

, ©NINJANERD 2024/2025. YEAR PUBLISHED 2024.
5. Teratogenesis

6. Adverse biotransformation reactions

Why does drug variability exist - ✔✔1. Genetic Factors

2. Environmental factors

3. Diseased states (cardiovascular or kidney disease for example)

4. Altered Physiological state

-pregnant or elderly

5. Other drugs present (competition)

The process of developing a new drug - ✔✔1. Pre-clinical testing

-safety and potential efficacy in lab animals



2. Phase I Clinical Trial

-safety and tolerability in healthy volunteers



3. Phase II

-effectiveness and safety in a small number of patients



4. Phase III

-effectiveness and safety in a large number of patients

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