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PHAR 100 Exam Questions and Answers 100% Solved | Graded A+

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PHAR 100 Exam Questions and Answers 100% Solved | Graded A+ What 3 civilizations were mentioned in the module about the history of drugs and what drug was associated with them? - Ancient Greece (opium and codeine), Ancient China (ma Huang), and Ancient Egypt (purgatives) What poisons were men...

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  • November 1, 2024
  • 28
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • PHAR 100
  • PHAR 100
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©NINJANERD 2024/2025. YEAR PUBLISHED 2024.
PHAR 100 Exam Questions and Answers

100% Solved | Graded A+


What 3 civilizations were mentioned in the module about the history of

drugs and what drug was associated with them? - ✔✔Ancient Greece

(opium and codeine), Ancient China (ma Huang), and Ancient Egypt

(purgatives)

What poisons were mentioned in the module? - ✔✔Curare and Ergot

What is peyote? - ✔✔Peyote is a small, spineless cactus, and has a

mescaline which causes halluciantions

Who invented complexes of arsenic and organic molecules which later led

to the cure for Syplihlis in 1900s - ✔✔Paul Ehrlich

who introduced sulfa drugs in 1930s - ✔✔Gerhard Domagk

Who created penicillin in 1940s - ✔✔Alexander Fleming

Who created streptomycin in 1950s - ✔✔Selman Waksman

,©NINJANERD 2024/2025. YEAR PUBLISHED 2024.
What are the 5 steps of drug development - ✔✔Basic research, Preclinical

trials, Clinical trials, Health Canada review and manufacturing, and post

market surveillance and phase IV clinical trial

What 2 parts are in basic research and drug discovery - ✔✔Identification of

target, and studying the target

What are the 2 types of preclinical trials - ✔✔Toxicology studies, and

pharmacology studies

What 3 things are a part of clinical trials? - ✔✔Proof of safety,

Methodology, and investigation

What are the 3 pahses of clinical trials - ✔✔Phase 1 - lookds at ADME in

small group

Phase 2 - looks at patients to see effects in medium sized group

Phase 3 - RCT with 1000's of people

What is a gold standard drug? - ✔✔A drug which is the current treatment

for a condition

Why is it safe to take a drug which was just rebranded? - ✔✔The rebrand

drug and original must be bioequivalent which basically means the same.

The only thing that changes is the name.

, ©NINJANERD 2024/2025. YEAR PUBLISHED 2024.
Why are post-market surveillance and phase IV clinical trials so important -

✔✔Helps identify and new side effects specific to certain people.

What are drug targets? - ✔✔Usually receptors and drug goes towards this

thing to produce an effect as either an agonist or antagonist

What is an agonist? - ✔✔It is a drug that is capable of binding to, and

activating, a receptor

What is an antagonist? - ✔✔They block the action of an agonist getting to

the receptor to elicit a response, therefore no response is made

What is the efficacy of a drug? - ✔✔the maximal response produced by the

drug

How is efficacy different from potency? - ✔✔Potency is the amount of a

substance needed to give a response, while efficacy is the max response

What is ED50? - ✔✔effective dose for 50% of the population

What has a greater efficacy, morphine or aspirin? - ✔✔Morphine since it

has a higher maximum effect

What is the therapeutic range? - ✔✔The range where the drug is above the

minimum concentration for an effect but below the maximum which would

produce a toxic effect

What is ADME - ✔✔absorption, distribution, metabolism, excretion

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