LAB CE EXAM QUESTIONS AND ANSWERS
How is valproic acid administered? - Answers- Oral preparation
Direct microscopic examination of a wet preparation of vaginal discharge provides the
simplest rapid diagnostic test for which of the following organisms? - Answers-
Trichomonas vaginalis because it can be seen on wet mount specimens.
What is true about Lupus Anticoagulant (LA) - Answers- LA is an immunoglobulin, acts
as an inhibitor of phospholipid-dependent coagulation in vitro
Two main compartments of the bone marrow - Answers- vascular sinuses and
hematopoietic cords.
Vascular sinuses - Answers- specialized spaces that contain blood vessels which allow
for the hematopoietic cells to enter circulating blood.
The immunoglobulin class responsible for the etiology of Hemolytic disease of the Fetus
and Newborn is - Answers- IgG MW:150,000 and can travel through the placenta
Which of the following reside in macrophages - Answers- Leishmania amastigote.
Intracellular hemoflagellate always assume amastigote stage
Leishmania promastigoTes - Answers- phagocytksed by macrophages and transform
into amastigotes.
Contains the most Factor VIII concentration relative to the unit volume - Answers-
Cryoprecipitate AHF
Cryoprecipitate AHF - Answers- cold-insoluble portion of the plasma that remains after
FFP has been thawed. Rich in VWF, fibrinogen, Factor VIII, fibronectin, and factor XII
Teardrop cells - Answers- predominant abnormal finding in idiopathic myelofibrosis,
thalassemia syndromes, drug-induced Heinz body formation, iron deficiency and others
Target cells - Answers- increase in RBC surface membrane. Many types of anemia,
hemoglobinopathies, thalassemia and liver disease
Elliptocytes - Answers- hemoglobin concentrated at both ends, Hereditary elliptocytosis
with 25-90% of cell in this shape
What is the predominant abnormal erythrocyte morphology associated with idiopathic
myelofibrosis? - Answers- Teardrop cells
,Tricyclic Antidepressants are used to treat insomnia, depression, extreme apathy, and
loss of libido. All f the following are TCAs, except? - Answers- Clozapine, which is an
antipsychotic.
Which of the following serological tests would be used for the diagnosis of Q-fever? -
Answers- EIA or indirect immunofluorescence.
Weil-Felix test - Answers- detects cross reacting rickettsia antibodies by using Proteus
vulgaris
Quellung test - Answers- Serotyping of the pneumococcus based on capsular
polysaccharide is performed in
Plasmin is known to degrade Factors Va, VIIIa, and GPIb. What other substance is it
known to digest? - Answers- Fibrin. Conversion of plasminogen into plasmin will result
in the digestion of fibrin clots, which is the main purpose of the fibrinolytic pathway
Which of the following is the most common type of autoimmune hemolytic anemia -
Answers- Warm autoimmune hemolytic anemia. 70% of cases
All of the following would result in a rejection of an analytical run under the Westgard
rules, except: - Answers- One control observation exceeding the mean by 2.5 SD
DAT is most unreliable when diagnosing hemolytic disease of the fetus and newborn
due to which blood group system - Answers- ABO, DAT is neither strongly nor
consistently positive. It is reliable for antibodies in the Duffy, Rh, and Kidd antibody
systems
Which of the following statements about lipoproteins is FALSE - Answers- Elevated LDL
causes a decreased risk of atherosclerosis
Which of the following lipid results would be expected to be most falsely elevated on a
serum specimen from a non-fasting patient - Answers- Triglycerides. Show marked
elevation after an individual eats.
A 42 year old chain smoker experienced an increase in cough, sputum production, and
intermittent shortness of breath for over one week. A diagnosis of chronic bronchitis with
acute exacerbation was made. The image shows a gram stain of an early morning,
spontaneously expectorated sputum. Based on the pleomorphic coccobacilli shown in
the gram stain, what is the most likely cause of the exacerbation? - Answers-
Haemophilus influenzae. Tiny coccobacilli.
What is the approximate volume of spinal fluid in an adult - Answers- 90-150 mL, 10-60
in neonates
, All of the following would be considered a part of the body's cellular immune system
except - Answers- Thrombocytes, they're involved in hemostasis, not immunity. Mast
cell release inflammatory mediators.
What procedure should be followed when one cross-matched unit out of five is
incompatible at the antiglobulin phase? - Answers- Perform a direct antiglobulin test on
the compatible unit
Which of the following is an example of proper transfusion practices regarding fresh
frozen plasma? - Answers- Should be transfused within 24 hours of thawing
An instructor wants to assess a learner's cognitive and psychomotor skills in
immunohematology. The best form of testing for this scenario would be - Answers-
Practical tests
Which of the following is currently considered to be a good test for screening persons
for hereditary hemochromatosis due to sensitivity and specitivity for iron overload? -
Answers- Transferrin saturation. >45% is diagnostic. Serum levels are elevated, but not
sufficient alone
Which of the following statements are true about anti-H? - Answers- Anti-H reacts more
strongly with group A2 cells than group A1.
0>A1>B>A2B>A1>A1B
Kliger iron agar shows an entirely yellow slant and butt, indole tube shows a layer of red
color, Simmons citrate tube is green in color. - Answers- Escherichia coli
The pl of a protein is 9.2. This protein is placed in an electrical field where a bugger sets
the pH at 10.0. Select the correct statement regarding the electrophoretic migration of
this protein. - Answers- This protein will have a net negative charge and will migrate
toward the anode, the positively charged electrode. If the pH for electrophoresis is
above the pl of a protein, the protein will have a net negative charge. Negative ions,
migrate towards the anode.
All of the following are causes of hemolytic anemia, except - Answers- iron deficiency
anemia
Sudan III will confirm the presence of: - Answers- fat. Oil red O is another stain.
Monocytes - Answers- nongranular and the largest WBC. Folded nucleus and irregular
shape. Cytoplasm stains gray-blue and contains vacuoles.
Lymphocytes - Answers- nongranular white cells with a large dark staining nucleus and
very little cytoplasm which stains light blue. Smallest white cells.
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