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Exam 3: NURS5334/ NURS 5334 (Latest 2024/ 2025 Update) Advanced Pharmacology for Nurse Practitioners Guide| Qs & As| 100% Correct| Grade A
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Exam 3: NURS5334/ NURS 5334 (Latest 2024/ 2025 Update) Advanced Pharmacology for Nurse Practitioners Guide| Qs & As| 100% Correct| Grade A
Q: How does metformin work?
Answer::
o Inhibits glucose production in the livero Reduces glucose absorption in the guto Sensitizes insulin receptors ...
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1. Exam (elaborations) - Exam 3: nurs5334/ nurs 5334 (latest 2024/ 2025 update) advanced pharmacology for nurs...
2. Exam (elaborations) - Exam 3: nurs5334/ nurs 5334 (latest 2024/ 2025 update) advanced pharmacology for nurs...
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1. Exam (elaborations) - Exam 3: nurs5334/ nurs 5334 (latest 2024/ 2025 update) advanced pharmacology for nurs...
2. Exam (elaborations) - Final exam: nurs5334/ nurs 5334 (latest 2024/ 2025 update) advanced pharmacology for ...
3. Exam (elaborations) - Exam 3: nurs5334/ nurs 5334 (latest 2024/ 2025 update) advanced pharmacology for nurs...
4. Exam (elaborations) - Final exam: nurs5334/ nurs 5334 (latest 2024/ 2025 update) advanced pharmacology for ...
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1. Exam (elaborations) - Exam 3: nurs5334/ nurs 5334 (latest 2024/ 2025 update) advanced pharmacology for nurs...
2. Exam (elaborations) - Exam 2: nurs5334/ nurs 5334 (latest 2024/ 2025 update) advanced pharmacology for nurs...
3. Exam (elaborations) - Exam 1: nurs5334/ nurs 5334 (latest 2024/ 2025 update) advanced pharmacology for nurs...
4. Exam (elaborations) - Final exam: nurs5334/ nurs 5334 (latest 2024/ 2025 update) advanced pharmacology for ...
5. Exam (elaborations) - Exam 2: nurs5334/ nurs 5334 (latest 2024/ 2025 update) advanced pharmacology for nurs...
6. Exam (elaborations) - Exam 3: nurs5334/ nurs 5334 (latest 2024/ 2025 update) advanced pharmacology for nurs...
7. Exam (elaborations) - Final exam: nurs5334/ nurs 5334 (latest 2024/ 2025 update) advanced pharmacology for ...
8. Exam (elaborations) - Exam 1: nurs5334/ nurs 5334 (latest 2024/ 2025 update) advanced pharmacology for nurs...
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Examl3:lNURS5334/lNURSl5334l(Latest
lUpdate)lAdvancedlPharmacologylforlNursel
PractitionerslGuide|lQsl&lAs|l100%lCorrect|
lGradelA
Q:lHowldoeslmetforminlwork?
Answer::
olInhibitslglucoselproductionlinlthelliverolReduceslglucoselabsorptionlinlthelgutolSensitizeslins
ulinlreceptorslinltargetltissuesl(fatlandlskeletallmuscle)lthuslincrease
glucoseluptakelandlresponseltolwhateverlinsulinlislavailable
Q:lMetforminlWhatlarelsideleffects?lBBlwarning?
Answer::
olGIleffects—diarrhea
olLacticlacidosis
Q:lHowldoeslalcoholleffect?
Answer::
Inhibitslthelbreakdownlofllacticlacid
Q:lWhatlareltheltherapeuticluseslotherlthanlDM?
Answer::
,olGestationalldiabetes
olPCOS
Q:lSulfonylureas
Answer::
olFirstlgeneration
lChlorpropamidel[Diabinese]
lTolazamidel[Tolinase]
lTolbutaminel[Orinase]
olSecondlGeneration:
lGlyburidel[Diabeta,lGlynase,lMicronase]lwithlmetforminl[Glucovance]
lGlypizidel(Glucotrol,lGlucotrollXL);lwithlmetforminl[metaglip])
lGlimepiridel(Amaryl;lwithlmetforminl[AmaryllM],lwithlpioglitazonel[Duetact]
withlrosiglitazonel[Avandaryl]
Q:lMOA?
~~~~~~~~~~~~
Mainlsideleffect?
Answer::
Promotelinsulinlrelease
~~~~~~~~
lHypoglycemia
lWeightlgain
Q:lHowldoeslcimetidineleffect?lBetalblocker?
Answer::
Cimetidine—intensifieslthelresponse
lBetalblockers—diminishlthelbenefitslbylsuppressinglthelinsulinlrelease
,Q:lMeglitinidesl(RepaglinidelandlNateglinide)
Answer::
olMOA—stimulatelpancreaticlinsulinlrelease
olDrug/Druglinteraction—gemfibrozil
Q:lThiazolidinedionesl(glitazones)
Answer::
Reducelglucosellevelslprimarilylbyldecreasinglinsulinlresistance
olOnlylindicationlisltypel2ldiabetes,lmainlylaslanladd-onltolmetformin
olRosiglitazonel[Avandia]:lRestrictedluse
olPioglitazonel[Actos]
olCanltheylbelusedlinlpatientlwithlCHF?
lNo
Q:lAlpha-glucosidaselinhibitorsl(AcarboselorlPrecose;lMiglitoll(glyset))
~~~~~~~~~~~~~~~~~~~~
Whatlraceslareltheselmoreleffectivelin?
Answer::
LatinoslandlAfricanlAmericans
Q:lDPP-4linhibitorsl(gliptins)
Answer::
MOA—promotelglycemiclcontrollbylenhancinglthelactionsloflthelincretinlhormonesland
theylstimulatelglucoseldependentlreleaseloflinsulin
lSuppresslyourlpost-prandiallreleaseloflglucagon
, Q:lWhatlislthel%loflA1Clreduction?
Answer::
0.5%
Q:lHowldoeslcolesevelamlworklinltreatmentloflDM?lBromocriptine?
Answer::
Colesevelam—bilelacidlsequestrantlusedltollowerlcholesterollandlhelpsllowerlblood
glucose
lManylwithldiabeteslalsolhavelhighlcholesterollsol2lbirds-1lstone
olBromocriptine—adjunctltoldietlandlexercisel(0.5%lreduction)
Q:lInjectables:
olAmylinlmemetics?
Answer::
Pramlintide
lSideleffects—hypoglycemialwhenlusedlwithlinsulin
lDrug/Drug—insulin
olGLP-1lreceptorlagonistsl(orlincretinlmimetics)
lCanlcauselmedullarylthyroidlcancer
Q:lWhatlisltreatmentlofldiabeticlketoacidosisl(DKA)?lHypoglycemia?
Answer::
olInsulinlreplacement,lreverselacidosislwithlbicarbonate,lreplacelwater,lsodium,
potassium,lnormalizelglucosellevels