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Parasitology Exam 2 (ZOO 4234) Part 2 Answered Correctly!!!
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Parasitology Exam 2 (ZOO 4234) Part 2 Answered Correctly!!!
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Parasitology Exam 2 (ZOO 4234) Part 2Answered Correctly!!!
TH1 cells mainly secrete: CORRECT ANSWERS IL-2, IFN-y, TNF, GM-CSF
IL-2 CORRECT ANSWERS growth factor for T and B cells; natural killer cells become
lymphokine-activated killer cells (LAK)
IFN-y CORRECT ANSWERS inhibition of TH2 cells, strong macrophage-activating
factor
TNF CORRECT ANSWERS major mediator of inflammation; high concentrations
increase synthesis of prostaglandis, resulting in fever
GM-CSF CORRECT ANSWERS granulocyte-macrophage colony-stimulating factor
TH2 cells mainly secrete: CORRECT ANSWERS IL-4, IL-5, IL-10
IL-4 CORRECT ANSWERS growth factor for B cells; suppresses TH1 cell production
IL-5 CORRECT ANSWERS stimulates B cells for growth, differentiation and production
of antibodies; activates eosinophils
IL-10 CORRECT ANSWERS inhibits TH1 cells and cytotoxic T cells, NK cells and
macrophage cytokine synthesis
Humoral immunity CORRECT ANSWERS based on antibodies on cell surface and in
body fluids (blood, lymph, etc.)
B cells CORRECT ANSWERS bind specific to free (soluble) antigen or particulate
antigen with its membrane bound antibody (B cell receptor); also serves as APC to TH
cells
B cells produced in CORRECT ANSWERS red bone marrow; immunoglobulin (Ig)
synthesis occurs
-tested for auto-reactivity by the immune system before leaving bone marrow
If B cells are highly reactive to self what occurs? CORRECT ANSWERS Clonal
deletion, receptor editing, anergy
Clonal deletion CORRECT ANSWERS removal, usually by apoptosis
Receptor editing CORRECT ANSWERS opportunity to rearrange their conformation via
RAG gene (recombination activating gene)
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