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RBC disorders Exam Study Guide Solutions

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RBC disorders Exam Study Guide Solutions MCV: Mean cell volume - ANSWER-The average volume per red cell, expressed in femtoliters, Hematocrit/number of erythrocytes MCH: Mean cell hemoglobin - ANSWER-The average mass of hemoglobin per red cell, expressed in picograms, Hemoglobin/number of eryt...

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  • October 31, 2024
  • 12
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • Red Blood Cells
  • Red Blood Cells
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RBC disorders Exam Study Guide

Solutions


MCV: Mean cell volume - ANSWER✔✔-The average volume per red cell, expressed in femtoliters,

Hematocrit/number of erythrocytes


MCH: Mean cell hemoglobin - ANSWER✔✔-The average mass of hemoglobin per red cell, expressed in

picograms, Hemoglobin/number of erythrocytes


MCHC: Mean cell hemoglobin concentration - ANSWER✔✔-The average concentration of hemoglobin in

a given volume of packed red cells, expressed in grams per deciliter, Hemoglobin

concentration/Hematocrit


RDW: Red cell distribution width - ANSWER✔✔-the coefficent of variation of red cell volume


Three causes of anemias - ANSWER✔✔-Blood loss (hemorrhage), Increased red cell destruction

(hemolysis), decreased red cell production


Small red blood cells are called and caused by - ANSWER✔✔-Microcytic (caused by iron deficiency,

thalassemia)




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, ©EMILLECT2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED

FIRST PUBLISH OCTOBER 2024




Large red blood cells are called and caused by - ANSWER✔✔-Macrocytic (caused by folate or B12

deficiency)


Hereditary spherocytosis manifests as: - ANSWER✔✔-spherocytic shaped cells with anemia,

splenomegaly, and jaundice. There is both a dominant and recessive form (dominant mutation usually

due to ankkyrin) recessive is usually worse


Folate deficiency and B12 deficiency both interfere with what cellular process? - ANSWER✔✔-DNA

synthesis


What is the most common type of anemia in hospitalized patients? - ANSWER✔✔-Anemia of chronic

disease (induced by chronic inflammation)


What diseases are associated with anemia of chronic disease? - ANSWER✔✔-Microbial infections (ex.

Osteomyelitis, endocarditis), Chronic immune disorders (ex. Rheumatiod arthritis), Neoplasms (ex.

Hodgkin lymphoma)


How does folate deficiency differ from B12 deficency? - ANSWER✔✔-Neurologic abnormalities do not

occur with folate deficency


Unless otherwise suggested a defciency of B12 in the western world is caused by: - ANSWER✔✔-

pernicious anemia (i.e. inadequate absorption of b12, b12 need intrsinic factor for absorption)




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