NUR 4125 PATHOPHYSIOLOGY EXAM 2
QUESTIONS AND ANSWERS WITH
SOLUTIONS 2025
During,a,blood,transfusion,,a,client,begins,to,have,chills,,back,pain,,and,develops,a,fever.,The,nur
se,determines,the,client,is,experiencing,a,transfusion,reaction.,The,nurse,educates,the,client,ab
out,transfusion,reactions.,Which,statement,indicates,the,cause,of,the,reaction?
A.,There,is,no,known,cause,for,blood,reactions.,Even,if,the,correct,haplotypes,are,identified,the,
body,can,still,activate,the,immune,system,and,reject,the,blood.
B.,Blood,is,typed,based,on,the,haplotype,compatibility.,A,reaction,occurs,when,the,blood,is,not,t
yped,correctly.
C.Each,person,has,two,HLA,haplotypes,that,identify,human,cells.,
Blood,typing,involves,the,identification,of,these,haplotypes,(ABO,compatibility).,The,closer,the,
matching,of,HLA,types,,the,greater,is,the,probability,of,identical,antigens,and,the,lower,the,chan
ce,of,rejection.,A,reaction,occurs,if,the,immune,system,views,the,HLA,types,as,foreign.
D.,Human,leukocyte,antigens,(H,-
,ANSWER,C.,Each,person,has,two,HLA,haplotypes,that,identify,human,cells.,
Blood,typing,involves,the,identification,of,these,haplotypes,(ABO,compatibility).,The,closer,the,
matching,of,HLA,types,,the,greater,is,the,probability,of,identical,antigens,and,the,lower,the,chan
ce,of,rejection.,A,reaction,occurs,if,the,immune,system,views,the,HLA,types,as,foreign.
Chapter,11:,Innate,and,Adaptive,Immunity,-,Page,297
A,client,with,infectious,mononucleosis,asks,the,nurse,why,the,lymph,nodes,are,enlarged.,Which,
statement,is,the,nurse's,appropriate,response?
A.,"Your,lymph,nodes,are,blocked,and,need,to,be,drained."
B.,"Your,lymph,nodes,multiply,to,fight,infection."
C.,"Your,lymph,nodes,trap,and,destroy,viruses."
C.,"Your,lymph,nodes,are,infected,and,should,be,removed.",-
,ANSWER,C.,"Your,lymph,nodes,trap,and,destroy,viruses."
Chapter,11:,Innate,and,Adaptive,Immunity,-,Page,297
,Which,client,is,at,the,greatest,risk,for,developing,an,intracellular,pathogen,infection?
A.,A,client,with,breast,cancer,who,has,a,WBC,count,of,8000
B.,A,teenager,who,attends,a,crowded,high,school
C.,A,client,with,AIDS,who,has,a,decreased,CD4+,TH1,count
D.,A,client,with,hyperthyroidism,who,has,received,treatment,with,radioactive,iodine,-
,ANSWER,C.,A,client,with,AIDS,who,has,a,decreased,CD4+,TH1,count
Chapter,11:,Innate,and,Adaptive,Immunity,-,Page,295
A,client,is,brought,to,the,physician's,office,with,a,raised,,red,macular,rash,on,the,trunk,and,arms,
accompanied,by,a,fever.,A,diagnosis,of,measles,is,made.,Which,type,of,immunity,does,this,disea
se,process,provide?
A.,Passive,artificial,immunity
B.,Active,artificial,immunity
C.,Active,natural,immunity
D.,Passive,natural,immunity,-,ANSWER,C.,Active,natural,immunity
Chapter,11:,Innate,and,Adaptive,Immunity,-,Page,298
A,client,has,recently,received,a,pneumococcal,vaccine,and,the,client's,B,cells,are,consequently,p
roducing,antibodies.,Which,cells,may,enhance,this,production,of,antibodies?
A.,Cytotoxic,T,cells
B.,Natural,killer,cells
C.,Regulatory,T,cells
D.,Helper,T,cells,-,ANSWER,D.,Helper,T,cells
Chapter,11:,Innate,and,Adaptive,Immunity,-,Page,288
,The,cells,that,mediate,humoral,immunity,do,so,because,they,are,capable,of,producing:
A.,Stem,cells
B.,Platelets
C.,Helper,T,cells
D.,Antibodies,-,ANSWER,D.,Antibodies
Chapter,11:,Innate,and,Adaptive,Immunity,-,Page,284-287
A,client,who,was,exposed,to,hepatitis,A,at,a,local,restaurant,has,recovered,from,the,disease.,At,t
he,annual,physical,,the,client,asks,whether,to,get,the,hepatitis,A,"shot.",How,will,the,nurse,resp
ond,,based,on,the,concepts,of,adaptive,immunity?
A.,"Yes,,because,you,could,get,a,worse,case,the,next,time,you,are,exposed."
B.,"I,would,not,recommend,getting,it;,the,vaccine,can,damage,your,liver."
C.,"No,,because,having,an,active,case,,you,have,already,developed,antibodies,against,hepatitis,A
."
D.,"Of,course.,The,virus,changes,every,year.",-
,ANSWER,C.,"No,,because,having,an,active,case,,you,have,already,developed,antibodies,against,
hepatitis,A."
Chapter,11:,Innate,and,Adaptive,Immunity,-,Page,284
A,client,is,being,evaluated,for,atopic,dermatitis,possibly,caused,by,a,latex-
related,allergic,reaction.,The,nurse,will,review,which,lab,results,to,determine,if,an,allergy,is,pres
ent?
A.,Neutrophils
B.,Serum,IgE
C.,Basophils
D.,Serum,IgG,-,ANSWER,B.,Serum,IgE
, Chapter,11:,Innate,and,Adaptive,Immunity,-,Page,293
A,newborn,has,been,lethargic,and,is,not,nursing,well.,Testing,of,cord,blood,done,at,birth,reveals,
the,presence,of,IgM.,How,should,the,nurse,interpret,this,finding?
A.,IgM,in,the,blood,means,the,newborn,may,be,allergic,to,breast,milk.
B.,The,presence,of,IgM,suggests,the,newborn,has,an,infection.
C.,IgM,is,usually,only,found,in,saliva,so,the,specimen,must,be,contaminated.
D.,All,newborns,have,IgM,in,their,blood,so,this,is,a,normal,finding.,-
,ANSWER,B.,The,presence,of,IgM,suggests,the,newborn,has,an,infection.
Chapter,11:,Innate,and,Adaptive,Immunity,-,Page,299
The,nurse,is,reviewing,the,functions,of,immunoglobulins,and,determines,which,immunoglobulin
,is,associated,with,its,correct,action?
A.,IgE,,functions,as,a,receptor,for,antigen.
B.,IgD,,prevents,the,attachment,of,viruses,and,bacterial,to,epithelial,cells.
C.,IgM,,the,first,antibody,to,be,produced,by,a,developing,fetus.
D.,IgA,,plays,a,role,in,B-cell,differentiation,-
,ANSWER,C.,IgM,,the,first,antibody,to,be,produced,by,a,developing,fetus.
Chapter,11:,Innate,and,Adaptive,Immunity,-,Page,293
An,obstetrics,nurse,is,counseling,an,expectant,mother.,The,mother,is,concerned,about,letting,pe
ople,hold,her,baby,once,the,baby,is,born,,fearing,that,the,infant,will,get,sick.,What,should,the,n
urse,explain,to,the,mother?
A.,The,innate,immune,system,will,protect,the,baby.
B.,IgA,that,is,present,at,birth,,and,which,originates,with,the,mother,,will,protect,the,baby,
C.,Maternal,immunoglobulins,cross,the,placenta,and,protect,the,newborn,early,in,life.