Exam (elaborations)
CMN 548 Unit 5 Exam Questions and Complete Solutions Graded A+
- Course
- Institution
CMN 548 Unit 5 Exam Questions and Complete Solutions Graded A+
[Show more]
Content preview
CMN 548 Unit 5 ExamQuestions and Complete
Solutions Graded A+
Potency - Answer: refers to the relative dose required to achieve certain effects, not to the efficacy of a
drug
Agonist (full agonist) - Answer: A drug that binds to a specific receptor producing an effect identical to
that usually produced by the neurotransmitter affecting that receptor
Pharmacodynamics - Answer: The time course and intensity of a drug's effect/what the drug does to the
body
Pharmacokinetics - Answer: What the body does to a drug
Tolerance - Answer: Develops over time a need to use increased doses of a medication/drug to maintain
a clinical effect. Or, a decreased sensitivity to adverse effects of a drug
Stevens-Johnson Syndrome - Answer: A systemic, immune-mediated reaction that can be fatal or result
in permanent scarring or blindness
Antagonist - Answer: A compound that blinds to a receptor that blocks or reduces the action of another
substance at the receptor site
Hyponatremia - Answer: Common symptoms of this medication side effect include confusion, agitation,
and lethargy. (tx with oxcarbazepine & SSRIs)
Therapeutic index - Answer: ratio of the median toxic dose to the median effective dose
,Somnolence - Answer: Daytime sleepiness
Black Box Warning - Answer: This warning reflects that a medication may cause a serious or even life-
threatening side effect
Partial or Mixed Agonist - Answer: A compound that elicits a partial pharmacological response at the
receptor site involved
Remission - Answer: The degree of improvement to below the syndromal threshold of a disorder
Paradoxical - Answer: A response to a drug that represents the clinical effect opposite of what is
expected
Inverse agonist - Answer: An agent that binds to the same receptor site as an agonist but produces the
opposite pharmacological effect
4 major transmitters - Answer: Dopamine, Serotonin, GABA, Norepinephrine
Dopamine transmitter affects? - Answer: affects mood, Psychosis, ADHD, Addiction
Serotonin transmitter affects? - Answer: Depression, aggression, OCD, Panic, GAD, Social Anxiety, PTSD,
Violence, Sexual dysfunction, substance addiction
Norepinephrine affects? - Answer: Affects mood, anxiety, psychosis, ADHD (part), drug withdrawal
GABA affects? - Answer: Fear, anxiety, worry
Irreversible MAOIs Types - Answer: MAOa and MAOb
, Irreversible MAOIs medications - Answer: Phenelzine (Nardil)
isocarboxazid (Marplan)
tranylcypromine (Parnate)
A single dose of MAOIs may persist in its inhibition of MAO for how long? - Answer: because they
irreversibly inactivate MAOs, the therapeutic effect of a single dose of irreversible MAOIs may persist for
as long as 2 weeks
What are the most frequent adverse effects of MAOIs? - Answer: orthostatic hypotension, insomnia,
weight gain, edema, sexual dysfunction
Reversible MAOIs (RIMAs) medications? - Answer: Moclobemide (Maerix)
How long will it take to recover MAO activity after a final dose of RIMA? - Answer: MAO activity recovers
completely 24-48 hrs after the last dose of a RIMA
MAOIs are used to treat what conditions? - Answer: depression
panic disorder
social phobia
bulimia nervosa
ptsd
anginal pain
atypical facial pain
migraine
adhd
idiopathic orthostatic hypotension
Depression associated with TBI
Treatment for MAOI induced orthostatic hypotension? - Answer: Avoid caffeine
intake of 2L of fluid/day
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller YourExamplug. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $14.49. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
83637 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now