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CHEM 310 Exam 2 || with Accurate Answers 100%.

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  • CHEM 310

Durkat 2014 Exam 2 pg 1 #. Serotonin 5-HT2 receptors are metabotropic receptor believed to be involved in the action of hallucinogens; they might also play a role in depression and psychosis. The dose-response curves below represent drugs A, B, and C that possess affinity for 5-HT2 receptors, but...

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  • October 31, 2024
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  • CHEM 310
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CHEM 310 Exam 2 || with Accurate Answers 100%.
Durkat
2014 Exam 2 pg 1
#. Serotonin 5-HT2 receptors are metabotropic receptor believed to be involved in the action of
hallucinogens; they might also play a role in depression and psychosis. The dose-response curves
below represent drugs A, B, and C that possess affinity for 5-HT2 receptors, but differ in their
intrinsic activity.

Effect vs. Log D Conc graph
Drug C (100% Effect with higher curve)
Drug A ( Lower curve)
Drug B (Flat line)

Drug A possesses an intrinsic activity α of __ and is best described as a(n) __

a) full agonist b) α < 0 c) second messenger
d) α = 0 e) antagonist f) first messenger
g) allosteric modulator h) partial agonist
i) α = 1 j) α > 10 k) 0 < α < 1
l) inverse agonist correct answers k) 0 < α < 1

h) partial agonist

Durkat
2014 Exam 2 pg 1
#. Serotonin 5-HT2 receptors are metabotropic receptor believed to be involved in the action of
hallucinogens; they might also play a role in depression and psychosis. The dose-response curves
below represent drugs A, B, and C that possess affinity for 5-HT2 receptors, but differ in their
intrinsic activity.

Effect vs. Log D Conc graph
Drug C (100% Effect with higher curve)
Drug A ( Lower curve)
Drug B (Flat line)

Drug B possesses an intrinsic activity α of __ and is best described as a(n) __

a) full agonist b) α < 0 c) second messenger
d) α = 0 e) antagonist f) first messenger
g) allosteric modulator h) partial agonist
i) α = 1 j) α > 10 k) 0 < α < 1
l) inverse agonist correct answers d) α = 0

e) antagonist

, Durkat
2014 Exam 2 pg 1
#. Serotonin 5-HT2 receptors are metabotropic receptor believed to be involved in the action of
hallucinogens; they might also play a role in depression and psychosis. The dose-response curves
below represent drugs A, B, and C that possess affinity for 5-HT2 receptors, but differ in their
intrinsic activity.

Effect vs. Log D Conc graph
Drug C (100% Effect with higher curve)
Drug A ( Lower curve)
Drug B (Flat line)

Drug C possesses an intrinsic activity α of __ and is best described as a(n) __

a) full agonist b) α < 0 c) second messenger
d) α = 0 e) antagonist f) first messenger
g) allosteric modulator h) partial agonist
i) α = 1 j) α > 10 k) 0 < α < 1
l) inverse agonist correct answers i) α = 1

a) full agonist

Durkat
Ehrlich is best known for introduction of which concept:
a) receptive substance
b) intrinsic activity
c) lock and key
d) ternary complex correct answers c) lock and key

Sakagami
1. Choose the CORRECT statement. Inhaled drug delivery
a. Can be used to deliver drugs for both local and systemic actions
b. Is generally achieved by gases or vapors generated from devices
c. Requires greater doses for drug action in lungs, compared to oral dosage forms
d. Results in slower onsets of drug action in lungs, compared to oral administration correct
answers a. Can be used to deliver drugs for both local and systemic actions

2. Choose the FALSE statement. Metered dose inhalers (MDIs) ...
a. Require propellants to generate drug aerosols
b. Are presently the most widely used inhaler devices
c. Are not favorably chosen for patients having a difficulty in breath-actuation coordination
d. Are designed to generate drug aerosols in an aerodynamic size of greater than 10 µm correct
answers d. Are designed to generate drug aerosols in an aerodynamic size of greater than 10 µm

Sakagami
3. Which of the following inhaler devices is NOT presently developed?

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