TEST BANK
INTRODUCTION
TO CLINICAL
PHARMACOLO
GY 11TH
EDITION BY
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, Chapter 01:
Pharmacology and
the Nursing Process
in LPN Practice
What is the name
drug that causes
the-drug-induced
liver disease (DILI)
and the name of
variant associated
with this DILI?
Flucoxacillin and
HLA-B *5701
, drug toxicity that
induces an
abnormal, life-
threatening
episode/ADR of the
polymorphic
ventricular
tachycardia that you
might be able to see
in ECG record
Torsades de
Pointes
What is the name of
drug that was
historically the first
non-sedating
antihistamine under
the brand name of
Seldane, but
subsequently
withdrawn from the
market due to the
risk of drug-
induced
arrhythmias?
Terfenadine
What is the
definition of
clinical
pharmacology?
A discipline
spanning the
spectrum of drug
delivery, drug
development, drug
utilization, and drug
regulation
What are the words
for the following
blanks?
Clinical
Pharmacology is
aimed at advancing
therapeutics in
humans with
mechanistic
understanding of
drug actions _____
and drug
, trial? one tenth of
LD50 for cancer or
phytotoxins
What are the
professional goals
of clinical
pharmacologists?
Discover, develop
and evaluate new
medicines, regulate
their use
Optimize the use of
existing medicines,
find new
indications
Define the basis for
variability in
therapeutic and
toxic responses to
medicines
What is the
measurement to see
whether some
toxicities can be
managed and may
be acceptable?
risk/benefit ratio
What is the
characteristic of
Risk/Benefit ratio?
It is contextual,
which tells you it is
depending on the
drug and disease
that we intend to
treat
For example, it is
not the same to
consider potentially
serious toxicity for
a drug intended to
treat HYT, which is
a medical condition
that needs lifelong
therapy, compared
to treatment of
cancer, a disease