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PSIO 303 Exam Questions and Answers

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PSIO 303 Exam Questions and Answers Which of the following is an accurate statement about signal transduction? A. A chemical messenger produced by one cell in a tissue that acts on an adjacent cell in the tissue is an example of endocrine communication. B. Only the amino acids tyrosine, serine,...

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  • October 30, 2024
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PSIO 303 Exam Questions and Answers


Which of the following is an accurate statement about signal transduction?




A. A chemical messenger produced by one cell in a tissue that acts on an adjacent cell in the tissue is an

example of endocrine communication.




B. Only the amino acids tyrosine, serine, and alanine in signaling proteins undergo phosphorylation and

dephosphorylation.




C. Phosphorylation of an intracellular protein can result in either activation or inactivation of that

protein.




D. A doubling of hormone binding to its plasma membrane receptors will cause a doubling of a cellular

response - ANSWER✔✔-C. Phosphorylation of an intracellular protein can result in either activation or

inactivation of that protein.

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Oxidative stress...




A. is characterized by excess ROS production.




B. is associated with cell damage and impaired cell signaling.




C. can be caused by elevated blood glucose levels.




D. All of the above. - ANSWER✔✔-D. All of the above.


Which of the following second messengers is NOT produced via a GPCR coupled with the given G-

protein?




1. Gs: cAMP




2. Gi: cGMP

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3. Gq: DAG and Ca2+




4. Gt: GMP - ANSWER✔✔-2. Gi: cGMP


The infusion of an inhibitor of eNOSinto an individual would have what effect?




1. Increase blood flow and glucose transport into skeletal muscle




2. Decrease blood flow and glucose transport into skeletal muscle




3. Have no effect on blood flow and glucose transport into skeletal muscle - ANSWER✔✔-2. Decrease

blood flow and glucose transport into skeletal muscle


Insulin resistance of glucose disposal in skeletal muscle is associated with all of the following EXCEPT:




A. Impaired vasodilation in arterioles due to excessive eNOSactivation in smooth muscle cells

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B. Decreased tyrosine phosphorylation of IR and IRS-1




C. Enhanced IRS-1 serine phosphorylation by PKC θinitiated by excess plasma FFA




D. Less plasma membrane GLUT-4 due to decreased GLUT-4 translocation - ANSWER✔✔-A. Impaired

vasodilation in arterioles due to excessive eNOSactivation in smooth muscle cells


Insulin secretion from β-cells requires all of the following EXCEPT:




A. ATP production (primarily from glucose oxidation in mitochondria).




B. ATP-mediated opening of K+-channels and membrane hyperpolarization.




C. Opening of voltage-gated Ca2+-channels and Ca2+release from the ER.




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