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PSIO 303 BLOCK 2 L6 Exam Study Guide Solutions

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PSIO 303 BLOCK 2 L6 Exam Study Guide Solutions List and discuss the diagnostic characteristics of passive diffusion. - ANSWER-ALL channels, and SOME carriers, can only support NET transport DOWN the electrochemical gradient of their transported substrates One category of carrier can do somethi...

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  • October 30, 2024
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PSIO 303 BLOCK 2 L6 Exam Study Guide

Solutions


List and discuss the diagnostic characteristics of passive diffusion. - ANSWER✔✔-ALL channels, and

SOME carriers, can only support NET transport DOWN the electrochemical gradient of their transported

substrates




One category of carrier can do something no channel can




Support net movement of their substrates AGAINST and electrochemical gradient


List and discuss the diagnostic characteristics of carrier mediated transport - ANSWER✔✔-Saturability




At low concentrations, transport increases in almost direct proportion in increases in [S]


First-order function




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As [S] continues to increase, the rate of transport begins to approach a maximum value


At high enough substrate concentrations, the carrier-mediated process can be expected to 'saturate'


In the context of cellular physiology, describe the importance of the kinetic parameters J max and K t -

ANSWER✔✔-J max = maximal rate of a carrier-mediated transport system, product of the number of

transporters x the


turnover number


K t = equal to the substrate concentration that produces 'half-maximal' transport when the rate of

transport is


equal to J max /2)


Given either a Michaelis-Menton plot or an Eadie-Hofstee plot, deduce Jmax and Kt - ANSWER✔✔-

Michaelis-Menton equation: relationship between substrate concentration and the rate of transport

(revealing


the saturation of that rate) is generally described by the following equation:


J = rate of transport at a substrate concentration equal to (S)


J max = maximal rate of transport and reflects 'saturation' of the process.




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