1. Characteristics of ideal medication
Answer
Effectiveness Safety
Selectivity reversible predictable
easy to administer free from interactions low cost
chemical stability simple generic name
2. What properties of medications need to be considered when prescribed?-
Answer
Pharmacokinetics. Drugs in the same class (or different formulations of the same drug) may
have different bioavailability, dose-concentration curves and half-lives. ... Pharmacodynamics. ...
Therapeutic efficacy and safety ..... Cost-effectiveness.
3. Patient specific variabilities affecting response to medications
Answer
Variation in the response to equivalent drug concentrations arises because of various factors,
such as differences in receptor number and structure, receptor-coupling mech- anisms and
physiological changes in target organs resulting from differences in genetics, age and health.
4. Pharmacodynamics
Answer
what the drug does to the body
5. Pharmacokinetics
Answer
The process by which drugs are absorbed, distributed within the body, metabolized, and
excreted.
, 6. Pharmacotherapeutics
Answer
study of the use of drugs in treating disease
7. Half-life of a drug
Answer
is the time required for one-half of an administered drug to be lost through metabolism and
elimination; different for each drug
8. Routes of medication administration
Answer
oral, mucosal, topical, parenteral
9. Oral Medications negatives
Answer
(1) the layer of epithelial cells that lines the GI tract, and (2) the capillary wall. Because the walls
of the capillaries that serve the GI tract offer no significant resistance to absorption, the major
barrier to absorption is the GI epithelium. To cross this layer of tightly packed cells, drugs must
pass through cells rather than between them. For some drugs, intestinal absorption may be
reduced by PGP, a transporter that can pump certain drugs out of epithelial cells back into the
intestinal lumen.
Absorption Pattern
Because of multiple factors, the rate and extent of drug absorption after oral admin- istration can
be highly variable. Factors that can influence absorption include (1) the solubility and stability of
the drug, (2) gastric and intestinal pH, (3) gastric emptying
time, (4) food in the gut, (5) the coadministration of other drugs, and (6) special coatings on the
drug preparation.
10. benefits of oral route
Answer
•Easy to use
• Easy for self administration
• Wide variety of medications Cost
Reversability
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller gradexam. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $17.99. You're not tied to anything after your purchase.