A 46-year-old man is currently enrolled in a Phase 1 study of a
drug for severe diabetic neuropathy. While the study is ongoing,
a new drug becomes commercially available that may have an
equal or greater benefit to the subject. The investigator should
do which of the following?
-Tell the subject about the new drug but discourage him from
switching treatments until the study is completed
-Give the subject comprehensive information about the new
drug, including its side effects, and then allow this subject to
decide whether or not to withdraw from the research.
-Do not tell the subject about the new drug since physicians
have the right to try out new treatments with their patients
-Withhold this new information to avoid confusing the subject
with other treatment options or alternatives Correct Answer
Give the subject comprehensive information about the new drug,
including its side effects and then allow this subject to decide
whether or not to withdraw from the research.
A general requirement for informed consent is that no informed
consent may include any exculpatory language. Exculpatory
language is that which waives or appears to waive any of the
subject's legal rights or releases or appears to release those
conducting the research from liability for negligence. Which of
the following statements in a consent form is an example of
exculpatory language?
,-In the event of any injury, you may have related to this
research, you will be given medical treatment.
-You must provide blood samples that will be kept in a "bank"
for future research. Once you have provided these blood
samples, you cannot change your mind about being in the
research and have the sample removed from the "bank".
-Your participation in this research is voluntary. If you choose
not to participate or change your mind later, your decision will
not affect your relationship with your doctor or your right to
health car Correct Answer You must provide blood samples
that will be kept in a "bank" for future research. Once you have
provided these blood samples, you cannot change your mind
about being in the research and have the sample removed from
the "bank".
A group of graduate PT students wants to test the EMG
(electromyography) activity of the abdominal muscles during
lifting. When they recorded the activity of the first subject and
showed it to their faculty mentor, he noticed that the activity was
very high, and told students that something went wrong. In your
opinion, what would be the possible source of error?
-EMG machine is not working properly
-Graduate students don't know how to measure EMG
-The subject they measured really has high EMG
,-All of these are correct Correct Answer All of these are
correct
A group of graduate students is spending one morning a week
observing the behavior of teenage mothers during playtime at
the local park. After they noted several significant differences in
the mother-child interaction with this group as compared to
other mother-child interactions they have observed, they began
making some audiotapes of the conversations. Which of the
following statements is true regarding privacy and
confidentiality?
-The graduate students CANNOT use the information they
gathered since parents would consider this a violation of
privacy.
-The graduate students CAN use the information since no names
will be used to identify participants.
-The graduate students CAN use the information from their
observations and audiotapes without a specific consent form
since the park is a public place
-The graduate students CANNOT use the information since the
parents are all teenagers. Correct Answer The graduate
students CANNOT use the information they gathered since
parents would consider this a violation of privacy.
A hypothetical study concluded that exercise improved
functional outcomes more than massage in people with neck
, pain. This finding is consistent with which of the following
research design types?
-A design that describes the prevalence of neck pain in people
who exercise
-A design that tests the effectiveness of exercise for people with
neck pain
-A design that assesses the statistical relationship between neck
pain and exercise
-A design that tests the causes of neck pain in people who
exercise Correct Answer A design that tests the effectiveness
of exercise for people with neck pain
A non-probability selection method that involves using a "word-
of-mouth" technique to make eligible candidates aware of a
study is called:
A patient fell down two days ago and dislocated his left
shoulder. According to the ICF model, inability to feed himself
with spoon falls under what category:
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