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APHA NAPLEX QUESTIONS AND ANSWERS 2024
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APHA NAPLEX QUESTIONS AND ANSWERS 2024
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APHA NAPLEXWhich of the following is not a potential source of physical or chemical
incompatibility?
A. dilution of a drug in a cosolvent system into an aqueous solution
B. addition of a drug solution with a high pH into a solution with a low pH
C. adsorption of a lipid-soluble drug into the matrix of a polypropylene container
D. a photosensitive drug such as sodium nitroprusside is D5W exposed to light
E. leaching of phthalate plasticizer into the solution from a PVC container -
ANSWERS-C. Absoprtion of a lipid soluble drug into the matrix of PVC containers
does occur. Polypropylene and polyethylene contain little or not plasticizer
Which of the following radiopharmaceuticals is indicated to image beta-amyloid
neuritic plaques in patients exhibiting cognitive impairment?
A. Tc-99m DTPA
B. Tc-99m biscisate
C. In-111 DTPA
D. Florbetapir F-18 - ANSWERS-D. Florbetapir F-18 is the only one with the
indication. Tc-99m DPTA is used to evaluate patients for brain death and Tc-99m
bicisate is used for evaluation of stroke patients in the evaluation of brain death.
In-111 DTPA is indicated for cisternography studies
,Which of the following radiopharmaceuticals is a controlled substance?
A. I-123 ioflupane
B. Florbetapir F-18
C. Thallous chloride T1-201
D. Tc-99m exametazime - ANSWERS-A. I-123 ioflupane is the only one is a
controlled drug
Which of the following radiopharmaceuticals accumulates in viable myocardial via
the Na/K ATPase pump?
A. F-18 FDG
B. Tc-99m tertrofsmin
C. Rb-82 chloride
D. Tc-99m sestamibi - ANSWERS-C. F-18 FDG is transported via glucose
transporters, Tc-99m tetrofosmin and Tc-99m sestamibi enter the cell via passive
diffusion
Which of the following radiopharmaceuticals is a monovalent cation and a
potassium analog?
A. F-18 FDG
,B. Tc-99m tetrofosmin
C. Tc-99m sestamibi
D. Thallous chloride T1-201 - ANSWERS-D. F-18 FDG is a glucose analog; Tc-99m
tetrofosmin and Tc-99m sestamibi are monovalent cations but not potassium
analogs; thallous chloride T1-201 is a monovalent cation and a potassium analog
Which of the following PET radiopharmaceuticals is commercially available from a
generator?
A. F-18 FDG
B. I-23 ioflupane
C. Florbetapir F-18
D. Rb-82 chloride - ANSWERS-D. F-18 and I-123 are not available from a generator
Which of the following is a myocardial radiopharmaceutical that provides
information on both perfusion and left ventricular function?
A. Rb-82 chloride
B. Tc-99m tetrofosmin
C. F-18 FDG
D. Thallous chloride T1-201 - ANSWERS-B. F-18 FDG is an indicator of metabolism,
Rb-82 chloride and thallous chloride provide information on myocardial perfusion.
Tc-99m tetrofosmin provides information on both myocardial perfusion and left
ventricular fn
, An example of a diagnostic skeletal agent is
A. Tc-99m bicisate
B. Tc-99m MDP
C. Sr-82 chloride
D. Florbetapir F-18 - ANSWERS-B. Tc-99m bicisate and florbetapir F-18 are for CNS
imaging. Sr 82 chloride is a palliative therapeutic agent
What patient preparation is recommended for skeletal imaging if the patient's
condition permits?
A. bowel cleansing
B. hydration
C. thyroid blockade
D. sincalide administration - ANSWERS-B. Hydration is recommended.
Which of the following correctly characterizes Tc-99m HDP?
A. localizes in areas of high bone metabolic activity
B. limited to use in adult patients with metastatic lesions
C. frequent adverse reactions
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