Clozapine REMS Certification Exam Questions And Answers 100% Pass
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Course
Clozapine REMS Certification
Institution
Clozapine REMS Certification
Clozapine REMS Certification Exam
Questions And Answers 100% Pass
What are box warnings for clozapine? - answerNeutropenia
Orthostatic Hypotension
Bradycardia
Syncope
Seizure
Myocarditis
Cardiomyopathy
What group is clozapine not FDA approved for? - answerIncreased mortality in elderly pat...
T/F: Risk of neutropenia is greatest from years 1-2 of treatment. - answer✔False; risk is greatest
during first 18 months
T/F: Risk of neutropenia is not dose dependent. - answer✔True
For which conditions is clozapine contraindicated? - answer✔Photosensitivity
Vasculitis
Erythema multiforme
Stevens Johnsons syndrome
Hx of hypersensitivity to clozapine
What is the starting dose for clozapine? - answer✔12.5mg either qd or BID
Your patient taking clozapine starts showing lowered heart rate, dizziness, and chest pain. What
do you do? - answer✔If patients are showing symptoms of cardiac complications, discontinue
and obtain labs
What is the method of increasing the clozapine dose? - answer✔Increase in increments of 25-
50mg/day.
What is the clozapine target dose by the end of 2 weeks? - answer✔300mg to 450mg/day (in
divided doses)
What is the max daily dose of clozapine? - answer✔900mg/day
Weekly ANC monitoring for the first ___ months, then every ___ weeks. - answer✔First 6
months
Then every 2 weeks
T/F: If ANC is greater than or equal to 1500 for the first year, monitoring can be reduced o every
4 weeks. - answer✔True
How is ANC calculated? - answer✔Total WBC count x Total percentage of neutrophils obtained
from differential
A patient taking clozapine presents with an ANC of 1300, what do you do? - answer✔- Continue
treatment
- Monitor ANC 3x/week
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