10/28/24, 8:39 AM 2024 Newest |NU 578 Unit 4 |2024-2025 UPDATE|COMPREHENSIVE MOST TESTED QUESTIONS AND VERIFIED SOLU…
2024 Newest |NU 578 Unit 4 |2024-2025
UPDATE|COMPREHENSIVE MOST TESTED
QUESTIONS AND VERIFIED SOLUTIONS|GET IT
100% ACCURATE!!
Terms in this set (65)
Insulin is used to treat all patients with type 1 and
many with type 2 diabetes. consists of two amino
acid chains (a acidic and b basic) linked by two
disulfide bridges. it is synthesized in the pancreas by
Insulin use b ce;;s within islets of langerhans. insulin is released
by rise in blood sugar (eating a. meal).
Anaolic reaction (insulin promotes conservation of
energy and buildup of energy stores)
Insulin promotes glucose into glycogen, amino
acids assembled into proteins, fatty acids into
Insulin metabolic actions triglycerides.
Insulin deficiency promotes glycogen into glucose,
proteins into amino acids, and fats into glycerol.
Biguanide
used for type 2 DM. oral anti diabetic. may be used
with other drugs. can be used for prevention of type
2 diabetes, GDM, PCOS.
Metformin use
Reduces GI absorbance of glucose and hepatic
production of glucose. Does not stimulate insulin
release from the pancreas.
, 10/28/24, 8:39 AM 2024 Newest |NU 578 Unit 4 |2024-2025 UPDATE|COMPREHENSIVE MOST TESTED QUESTIONS AND VERIFIED SOLU…
go to pancreas and increase insulin release.
DPP-4 Inhibitors (gliptins)
Example is Sitaglitpin
Example: empagliflozin
Sodium Glucose
increases urine excretion of glucose, taken PO,
cotransporter 2 inhibitors
reduces cardiovascular risk of type 2 diabetes.
(SGLT-2 inhibitors).
(gliflozins)
SE: yeast infections and genital gangrene
injectables that slow gastric emptying, causes
Incretin Mimetics ('tides)
weight loss and help an overwhelmed pancreas.
stimulate pancreas to release more insulin. range in
onset, duration, and potency and are only used for
type 2 diabetes. there are first generation and
second generation. second are more potent and
solfonylureas
doses are lower and drug drug interactions are less
common
AE: hypoglycemia
a glucosidase inhibitor
oral anti diabetic agent that inhibits breakdown of
oligosaccharides into monosaccharides. this delays
Acarbose digestion and prolongs absorption of carbs and
decreases postprandial hyperglycemia!!
ADR: FI upset and flatulence.
take this with first bite of each meal.
hypoglycemia caused by overdose.
Insulin Complications/
hypoglycemic agents (sulfonylureas, glinides, and
Drug Interactions
alcohol), hyperglycemia agents, b adrenergic
blocking agents.
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