Exam (elaborations)
NR 507 Midterm Exam Questions And Answers Latest Update
- Course
- NR 507
- Institution
- Chamberlain College Of Nursing
NR 507 Midterm Exam Questions And Answers Latest Update
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Solution 2024/2025Pepper
NR 507 Midterm Exam Questions And Answers
Latest Update
Hypersensitivity Type 1 ANS✔✔ Type 1: Allergic Reaction
Mediated by IgE
Inflammation due to mast cell degranulation
local symptoms: Itching, rash
Systemic symptoms: wheezing
Most dangerous form: anaphylactic reaction-systemic hypotension, severe
bronchoconstriction
Main treatment: epinephrine
Hypersensitivity Type 2 ANS✔✔ Type 2: Cytotoxic, tissue-specific (thyroid
tissue)
Primary effector cells: Macrophages
Can cause tissue damage or alter the function
Example: Graves disease (alters thyroid function but does not alter tissue)
Example: Incompatible blood type (cell/tissue damage)- Severe transfusion
reaction occurs and the transfused erythrocytes are destroyed by
agglutination or complement-mediated lysis
Hypersensitivity Type 2 and 3 difference ANS✔✔ Type 2: Organ-specific, the
antibody binds to an antigen on the cell surface
Type 3: Not organ-specific, the antibody binds to soluble antigen outside the
cell surface that was released into the blood or body fluids and then the
complex is distributed into tissues
, Solution 2024/2025
Pepper
Hypersensitivity Type 3 Examples ANS✔✔ Rheumatoid Arthritis:
antigen/antibodies are deposited in the joints
Systemic Lupus Erythematosus (SLE)- very closely related to autoimmunity-
antigen/antibodies deposit in organs that cause tissue damage
Scope of damage of SLE- Type 3 Hypersensitivity- autoimmune response
ANS✔✔ rash confined to cheeks (malar rash)
discoid rash (raised, patchy, scaly)
photosensitivity
oral/nasopharyngeal ulcers
hematologic disorders
immunologic disorders
non-erosive arthritis
serositis
renal disorder (proteinuria)
neurologic disorders (seizures)
antinuclear antibody (ANA)
Autoimmunity ANS✔✔ Familial
Affected family members may not have same dz, but several members may
have other disorders characterized by a variety of hypersensitivity reactions
that include autoimmune or allergic reactions
Associations with particular autoimmune diseases have been identified for a
variety of major histocompatibility complex (MHC) alleles or non-MHC genes
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