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Maryville University Pharmacology NURS 615 Exam 2 Questions and Answers (100% Pass) 2024 $13.49   Add to cart

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Maryville University Pharmacology NURS 615 Exam 2 Questions and Answers (100% Pass) 2024

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Maryville University Pharmacology NURS 615 Exam 2 Questions and Answers (100% Pass) 2024 What blood values should be monitored with carbamazepine (Tegretol)? P. 236-237 Answer CBC for agranulosytosis (leukopenia/ neutropenia), BMP, and liver function tests, monitored at baseline prior to adminis...

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  • October 26, 2024
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NurseFerian
Maryville University Nurs 615 Pharm Exam 2.pdf file:///C:/Users/HP/Desktop/New%20folder%20(4)/Maryville%20Univ




Maryville University Pharm Exam 2

Questions & Answers


1. What blood values should be monitored with carbamazepine (Tegretol)?

P. 236-237

Answer CBC for agranulosytosis (leukopenia/ neutropenia), BMP, and liver function

tests, monitored at baseline prior to administration and followed throughout

treatment



2. What is the pharmacodynamics of carbamazepine (Tegretol)? P. 235

Answer Carba-mazepine depresses transmission in the nucleus ventralis anterior of

the thalamus.This area is associated with the spread of seizure discharge. Exact

mechanism of action not known but may work by slowing sodium influx to the cortical

neurons thusslowing the spread of abnormal neuron activity.



3. What should families be taught regarding the monitoring of seizure ac-

tivity?
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,Maryville University Nurs 615 Pharm Exam 2.pdf file:///C:/Users/HP/Desktop/New%20folder%20(4)/Maryville%20Univ




Answer Seizure triggers, when to contact the physician, how to take medications

properly and that medication needs may change with patient growth (kids), need for

monitoring blood levels, signs of adverse drug reactions



4. What electrolyte imbalance is noted with the administration of topiramate

(Topamax)? P. 239

Answer Topiramate is a carbonic anhydrase inhibitor used for seizuresand migraines.

This can increase bicarb loss (via the kidneys) which decreases serum bicarb levels.

The result is hyperchloremic metabolic acidosis.



5. What is the pregnancy category for valproate?

Answer Pregnancy category D (FDAdropped Pregnancy category designations June

2015)



6. What instructions will you provide to a woman who wants to get pregnant

and has a seizure disorder controlled with valproate? P. 278-279

Answer She shouldbe advised to speak with her neurologist before trying to get

pregnant. Valproate isa known teratogen (it can lead to neural tube defects), but may

be taken after the first trimester if needed.
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7. What are the precautions and contraindications for the tricyclic antide-

pressants? P. 245-246

Answer Contraindicated with cardiovascular disorders (Direct alphaadrenergic

blocking effect and quinidine like effect on the myocardium). Use with caution in

those with glaucoma, prostatic hypertrophy, or urinary incontinence. Do not use in

combination with MAOIs. Two week washout period. Use with extreme caution in

pregnancy. Most significant risk is cardiac conduction disorder mostly inpeds and

elderly. May develop sinus tachycardia due to slowing of depolarization of the cardiac

muscle contributing to prolongation of the QRS complex and PR/QTinterval.Can

lower seizure threshold in those with seizure disorder.Use with extremecaution in the

elderly (norepinephrine effects in the elderly can result in confusion, orthostatic

hypotension, and falls. May develop tardive dyskinesia



8. Phenelzine (Nardil) is an MAO inhibitor.What are the cautions and con-

traindications? How is it used to treat recalcitrant depression? P. 248-249

Answer - Most commonly used for refractory unipolar depression. Irreversibly

inactivate the enzymes that metabolize norepinephrine, serotonin, and dopamine

which increases
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