RN 35B: Ch. 42 Cardiac Glycosides, Antianginals,
and Antidysrhythmics Test |Questions with 100%
Solutions/Verified Answers
dopamine and dobutamine - ANSWER IV Inotropic Drugs.
First-line drugs used to treat acute HF.
digoxin (Lanoxin)
[Action] - ANSWER Secondary drug for HF. Half-life is 30 to 40 hours; drugg
accumulation can occur. Pediatric doses are usually ordered in mcg in elixir form.
Action: increase myocardial contraction, which increases cardiac output,
improving circulation and tissue perfusion; heart rate is decreased because
of decreased conduction through AV node.
digoxin (Lanoxin)
[Drug Interactions] - ANSWER POTENT DIURETICS: loops [furosemide (Lasix)] and
hydrochlorothiazide promote the loss of potassium; hypokalemia increased the
effect of digoxin (digitalis toxicity).
CORTISONE PREPS: promote sodium retention and potassium excretion
(hypokalemia). [Pt. should consume foods rich in potassium or supplements; fresh
and dried fruits, fruit juices, vegetables, potatoes].
, ANTACIDS: decrease digitalis absorption; drugs should be staggered.
QUINIDINE: increase in digoxin serum level.
digoxin (Lanoxin)
[Herb Interaction] - ANSWER ST JOHN'S WORT: decreases absorption of digoxin,
decreasing serum level and effectiveness.
Digitalis Toxicity: serum greater than 2 ng/mL.
HF: lower levels should be obtained.
Atrial Fibrillation: higher levels should be obtained.
digoxin (Lanoxin)
[Effectiveness] - ANSWER Improvement and oxygenation includes decreased HR
& BP, decreased rales, increased urine output, and absence of side effects.
digoxin (Lanoxin)
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