Exam (elaborations)
PHC 4032 Chapter 16 Questions And Answers Latest Update
- Course
- PHC 4032
- Institution
- University Of South Florida
PHC 4032 Chapter 16 Questions And Answers Latest Update
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Solution 2024/2025Pepper
PHC 4032 Chapter 16 Questions And Answers
Latest Update
Antibiotics ANS✔✔ -single most important discovery for the treatment of
bacterial infections
-against life
-many are derived from natural products
-synthetic anti microbial
broad spectrum antibiotics ANS✔✔ -inhibitory to a large variety of Gram +
and - bacteria
-prescribed when seriously ill and causative bacteria is not identified
-ecological disruption
Narrow-spectrum antibiotics ANS✔✔ -inhibitory to a limited range of
bacteria
Mechanism of antibiotics ANS✔✔ - act by interfering with or disrupting vital
structures and metabolic pathways of the bacterial cell
Selective toxicity ANS✔✔ -antibiotic drugs target components of a microbe
that human cells do not have
-drug is toxic to microbes but not to human cells
, Solution 2024/2025
Pepper
Interference with cell wall synthesis ANS✔✔ - penicillin and cephalosporins
contain ring structures that associate and interfere with the enzymes
responsible for building the cross links during the cell wall synthesis-
-peptidoglycan affords protection against lysis
-transpeptidase provide the overall structural integrity of the cell wall
B-lactam antibiotics ANS✔✔ - results in the synthesis of a weakened cell
wall so that bacteria grow they lyse
-bactericidal antibiotics
-vancomycin (last antibiotic stronghold) interferes with the cross links
Interference with protein synthesis ANS✔✔ - protein synthesis is an integral
part of the cell's activity and culmination of the expression of DNA
Bacterial ribosomes ANS✔✔ -cytoplasmic structures on which protein
synthesis takes place
-targets for some antibiotics because differ in size and structure from
human ribosomes
-70s
Streptomycin ANS✔✔ -1944
-treatment of tuberculosis
Tetracyclines, chloramphenicol and erythromycin ANS✔✔ -interfere with
protein synthesis b binding to bacterial ribosomes
Tetracyclines ANS✔✔ - treatment of several tick borne diseases
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