Exam (elaborations)
RUSH – ADVANCED PHARMACOLOGY NSG 531 EXAM 4 LATEST UPDATED
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RUSH – ADVANCED PHARMACOLOGY NSG 531 EXAM 4 LATEST UPDATED...
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Ginseng - ANSWER FOR:Symptoms include nervousness, agitation, insomnia, diarrhoea, headaches, and
heart palpitations.
Avoid taking MAO inhibitors. Can change the effects of cardiac medicines. Can
increase the risk of bleeding when taken with blood-clotting medications.
CI: neuro, heart, MAO, bleeding, and coag medications.
Ma Huang (Ephedra) - ANSWER Dangerously raises blood pressure
and stimulates heart rate and CNS.
Associated with stroke, MI, and mortality.
Banned beyond 10 mg in the United States, except for traditional Asian
medicine.
Metabolife
Used for weight reduction, allergies, asthma, bronchitis, fever, and headache.
arginine - ANSWER: Arginine is used to treat heart and blood vessel diseases
such as congestive heart failure (CHF), chest discomfort, hypertension, and
coronary artery disease.
Do not use if.
Excess body acids
High potassium levels in the blood.
sickle cell anemia.
Heart attack within the last 30 days.
Renal tubular acidosis.
reduced renal function.
Do not use with nitro.
, pt. Education for herbs and nutrition - ANSWER 1. Herbs and minerals possess
bioactive qualities and share the same safety concerns as medicines.
2. Always contact a trusted source before contributing.
3. Consider while examining the credentials of the author of the website, what
proof is there to support their assertions, and are there any financial interests to
influence the claims of the author.
biological basis of drug/herb/nutrient interactions - ANSWER absorption
(changing pH or motility of the gastrointestinal tract)
Distribution (displacing drugs bound to plasma proteins)
Biotransformation (activating or suppressing CYP450 enzymes)
receptor binding (competitive and noncompetitive antagonism).
Gompertzian Kinetics - ANSWER Cancer cells lack normal regulatory factors,
resulting in aberrant proliferation.
You can go from 0 to 10^9 before symptoms appear.
This bounces because you're on and off of chemotherapy.
That is why we conduct numerous rounds—so you launch the next round of
treatment before you go back to where we started.
If you begin chemotherapy at a smaller tumor mass, you will obtain a better
response in a shorter period of time.
Drug resistance mechanisms - ANSWER decreased intracellular drug
concentration via drug inactivation processes, decreased absorption, and drug
efflux pumps
Drug target mutation results in a change in target.
Mutation in p53 causes insensitivity to apoptosis.
Chemotherapeutics: Antemetabolites block DNA synthesis enzymes.
works in the S phase.
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