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NUR 406 ( LATEST 2024 / 2025 ) AUTOIMMUNE | WITH 100% VERIFIED ANSWERS
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NUR 406 ( LATEST 2024 / 2025 ) AUTOIMMUNE | WITH 100% VERIFIED ANSWERS
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NUR 406 Autoimmune1. HLA system (human leukocyte antigen system)
Answer
Normal ability of immune system to differentiate self from non-self belongs what system?
2. HLA system (Human Leukocyte Antigen System)
Answer
Need 80% match of this for transplant
is encoded by major histocompatibility genes (MHC)
In order to elicit a T-system response, antigen must be processed & presented on surface of
phagocytic cell (Macrophage with MHC antigens)
Dual recognition system considered a security system T and B system with own recognition
systems
3. to create and immune response (dual recognition)
Answer
the B and T cells work together to
4. upregulated
Answer
HLA genes are in autoimmune illnesses,multiple cy-
tokines activated,inflammatory process
5. chemical messengers that activate the inflammatory response
Answer
what are cytokines?
6. blocking cytokines
Answer
what has been treatment approach for many auto-immune diseases
7. infliximab
, Answer
Tumor necrosis factor alpha as cytokine, so they developed
8. self tolerance
Answer
Disrupted through misrecognition by B or T cell such as a virus or drug complexed to carrier
molecule or cytokine
DNA usually in nucleus or mitochondria so if DNA outside these areas, immune system
identifies it as foreign and attacks it
9. B cell alteration theory
Answer
B cell immunity requires support of helper T cells therefore auto AB also require this process
For some reason the T system cannot suppress the B cell changes
New research focusing on boosting natural protective cells of immune system
10. T cell receptor alteration
Answer
T cells do not recognize the need to shut off as in a normal response resulting in an
autoimmune disease
11. 2 T helpers
Answer
1 supressor
Answer
what is the normal ratio of T help to suppressor cells?
12. T cells
Answer
HIV has decreased cells and suppressor cells predominate
causing various diseases due to immunosuppression
13. overactive T helper cells
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