Pharm Exam 3 Study Guide Questions with Accurate Answers Top Graded 2024
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Course
Pharm .
Institution
Pharm .
Binds to phospholipids in the fungal cell membrane, which increases permeability and allows leakage of essential cellular constituents.
a. Ketoconazole
b. Nystatin
c. Fluconazole
d. Clotrimazole
Clotrimazole
Punctures cell membrane
Binds to sterols in the fungal cell membrane, which increase...
Pharm Exam 3 Study Guide Questions
with Accurate Answers Top Graded 2024
Binds to phospholipids in the fungal cell membrane, which increases permeability and
allows leakage of essential cellular constituents.
a. Ketoconazole
b. Nystatin
c. Fluconazole
d. Clotrimazole
Clotrimazole
Punctures cell membrane
Binds to sterols in the fungal cell membrane, which increases permeability and allows
leakage of essential cellular constituents.
a. Ketoconazole
b. Nystatin
c. Fluconazole
d. Clotrimazole
Nystatin
Punctures cell membrane
Alteration of cell membrane permeability by inhibition of ergosterol synthesis
(enzymes); also inhibits sex steroid (testosterone) biosynthesis.
Ketoconazole
Punctures cell membrane AND prevent enzymes from carrying out normal functions of
the fungus
Alteration of cell membrane permeability by inhibition of ergosterol synthesis (enzymes).
Fluconazole
Prevent enzymes from carrying out normal functions of the fungus
Pharm Exam 3
,Pharm Exam 3
Absorbed poorly in the GI tract, so it can be used as a swish and spit; coats the mucous
membranes; available in suspensions, pastilles, vaginal tablets, oral tablets, and creams
a. Ketoconazole
b. Nystatin
c. Fluconazole
d. Clotrimazole
Nystatin
Suspensions and pastilles contain sugar, so instruct patients to swish and spit.
Used to treat and prevent oral Candidiasis.
Which antiviral is available OTC?
a. Penciclovir
b. Famciclovir
c. Acyclovir
d. Docosanol
Docosanol (Abreva)
Used for herpes simplex labialis
Available OTC topically
Decreases healing time for 1/2 day if used during prodromal stage
Which drug class used to treat HIV is incorporated into DNA polymerase so that the
synthesis of DNA is terminated?
a. Protease inhibitors
b. Nonnucleoside analogs/ Nonnucleoside reverse transcriptase inhibitors
c. Integrase inhibitors
d. Nucleoside analogs/nucleoside reverse transcriptase inhibitors
e. Fusion/Entry inhibitors
Nucleoside analogs/nucleoside reverse transcriptase inhibitors
DOES NOT affect HIV-infected cells.
Goal is to decrease HIV viral load and increase CD4 cell count.
Pharm Exam 3
, Pharm Exam 3
Includes drugs like Abacavir, Didanosine, Emtricitabine, Lamivudine, Stavudine, Tenofovir,
Zalcitabine, Zidovudine.
Which drug class used to treat HIV binds to DNA polymerase to prevent DNA synthesis?
a. Protease inhibitors
b. Nonnucleoside analogs/ Nonnucleoside reverse transcriptase inhibitors
c. Integrase inhibitors
d. Nucleoside analogs/nucleoside reverse transcriptase inhibitors
e. Fusion/Entry inhibitors
Nonnucleoside analogs/ Nonnucleoside reverse transcriptase inhibitors
DOES NOT affect HIV-infected cells.
Usually in combination with NRTIs and/or protease inhibitors.
Includes drugs like Delavirdine, Efavirenz, and Nevirapine.
Which drug class used to treat HIV prevents cleavage of protein precursors and
modulation of reverse transcriptase activity, preventing maturation of HIV-infected cells?
a. Protease inhibitors
b. Nonnucleoside analogs/ Nonnucleoside reverse transcriptase inhibitors
c. Integrase inhibitors
d. Nucleoside analogs/nucleoside reverse transcriptase inhibitors
e. Fusion/Entry inhibitors
Protease inhibitors
Interferes with the action of HIV-infected cells.
Includes drugs like Amprenavir, Atazanavir, Fosamprenavir, Indinavir, Nelfinavir,
Tipranavir, Ritonavir, Saquinavir.
Which drug class used to treat HIV interferes with the binding of an HIV virion into
human cells?
a. Protease inhibitors
b. Nonnucleoside analogs/ Nonnucleoside reverse transcriptase inhibitors
Pharm Exam 3
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