NSG 353 DRUGS FINAL EXAM QUESTIONS AND ALL CORRECT ANSWERS.
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Course
NSG 353
Institution
NSG 353
What is epinephrine's pharmacologic/therapeutic class? - Answer sympathomimetic/adrenergics
How is epinephrine administered? - Answer topically or injected
What is epinephrine's MOA? - Answer affects alpha1 by vasoconstriction for increased BP and decreased edema, affects beta1 by in...
NSG 353 DRUGS FINAL EXAM
QUESTIONS AND ALL CORRECT
ANSWERS.
What is epinephrine's pharmacologic/therapeutic class? - Answer sympathomimetic/adrenergics
How is epinephrine administered? - Answer topically or injected
What is epinephrine's MOA? - Answer affects alpha1 by vasoconstriction for increased BP and
decreased edema, affects beta1 by increasing cardiac output to increase BP, and affects beta2 by
bronchodilation
What is epinephrine's onset? - Answer rapid-12 min
What is epinephrine's duration? - Answer IV 20 min and IM/subQ/Inhal is 1-4 hours
What are epinephrine's indications? - Answer anaphylactic shock
What are epinephrine's adverse effects? - Answer any adverse effects of all 4 receptor types
What are epinephrine's significant drug/food interactions? - Answer MAO inhibitors (MAOI), tricyclics -
all will increase effects of epinephrine and alpha-adrenergic blockers, Beta-adrenergic blockers - all will
counteract epinephrine
How do we prepare epinephrine? - Answer IV doses must be less concentrated (high concentration can
be fatal IV)
Since epinephrine is a catecholamine, it... (3) - Answer can't be given orally, short duration, cannot
cross BBB
,What are epinephrine's contraindications? - Answer patients with angle closure glaucoma and patients
in NONanaphylactic shock
Whats is an epinephrine IM injection? - Answer epipen
How do we store an epipen? - Answer sensitive to heat and light so we store per manufacturers
specifications
What is albuterols pharmacologic/therapeutic class? - Answer beta 2 agonist
What is albuterols mechanism of action? - Answer causes smooth muscle relaxation and
bronchodilation by binding to beta 2 receptors
What is albuterols onset? - Answer inhalation 5-15 minutes
What is albuterols duration? - Answer 3-6 hours
What is albuterols indication? - Answer asthma
What are albuterols adverse effects? - Answer tremors and tachycardia that are minimal in appropriate
doses (jittery)
How do we administer albuterol? - Answer inhaled
Since albuterol is a noncatecholamine, it... - Answer can be given orally, longer duration, can cross BBB
What is prozasin's pharmacologic/therapeutic class? - Answer alpha-adrenergic antagonist,
bronchodilator
What is prozasin's MOA? - Answer Dilates both arteries and veins by blocking postsynaptic alpha1-
adrenergic receptors
, What is albuterol's MOA? - Answer binds to beta2-adrenergic receptors in airway smooth muscle
What is prozasin's onset? - Answer 15-30 minutes
What is prozasin's duration? - Answer 4-6 hours or more
What are prozasin's indications? - Answer Hypertension (approved), and benign Prostatic Hypertrophy
(off label)
What are prozasin's adverse effects? - Answer orthostatic hypotension, reflex tachycardia, nasal
congestion, inhibited ejaculation, and "first-dose" effect
How do we administer prozasin? - Answer orally
How do we mitigate the risk of first dose effect in prozasin? - Answer administering before bed
What is propranolol's pharmacologic/therapeutic class? - Answer non-selective beta-adrenergic
antagonist (beta blocker)
What is propranolol's MOA? - Answer Blocks stimulation of beta1 (myocardial) and beta2 (pulmonary,
vascular, and uterine)-adrenergic receptor sites.
What is propranolol's onset? - Answer 30 minutes
What is propranolol's duration? - Answer 6-12 hours
What are propranolol's indications? - Answer hypertension, angina pectoris, cardia dysrhythmias, and
myocardial infarction (MI)
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