All of the following are included in the peptide-loading complex except: - Correct Answer Calnexin
T-cell receptor delta-chain gene: - Correct Answer Positioned in the T-cell receptor alpha-chain locus between Va and Ja gene segments
Which of the following removes CLIP from MHC class II m...
VBSC 211 Exam 3 || ANSWERED CORRECTLY
All of the following are included in the peptide-loading complex except: - Correct Answer
Calnexin
T-cell receptor delta-chain gene: - Correct Answer Positioned in the T-cell receptor
alpha-chain locus between Va and Ja gene segments
Which of the following removes CLIP from MHC class II molecules? - Correct Answer
HLA-DM
CD8 T-cell subpopulations are specialized to combat ______ pathogens, whereas CD4
T-cell subpopulations are specialized to combat _____ pathogens: - Correct Answer
intracellular; extracellular
Which of the following describes the sequence of the events involved in processing of
peptides that will be presented as antigen with MHC class I? - Correct Answer
proteasome --> TAP 1/2 --> MHC Class I --> endoplasmic reticulum --> plasma
membrane
Which of the following describes the sequence of events involved in the processing of
peptides that will be presented as antigen with MHC class II? - Correct Answer
endocytosis --> protease activity --> removal of CLIP from MHC class II --> binding of
peptide to MHC class II --> plasma membrane
Which of the following cell types does not express MHC class I - Correct Answer
Erythrocyte
Which of the following cell types is not considered a professional antigen-presenting
cell? - Correct Answer neutrophil
The immunological consequence of severe combined immunodeficiency disease (SCID)
caused by a genetic defect in either RAG-1 or RAG-2 genes is? - Correct Answer Lack
of somatic recombination in T-cell receptor and immunoglobulin gene loci
Which of the following accurately completes this statement: "The function of ______ T
cells is to make contact with _____ and ____"? - Correct Answer CD4; B cells;
Stimulate B cells to differentiate into plasma cells
CD4; macrophages; enhance microbicidal powers of macrophages
CD8; virus-infected cells; kill virus-infected cells
Which of the following cell-surface glycoproteins is characteristic of stem cells, but stops
being expressed when a cell has committed to the T-cell developmental pathway? -
Correct Answer CD34
If a double-negative thymocyte has just completed a productive Beta-chain gene
rearrangement, which of the following describes the immediate next step in the
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