PSU VBSC 211: Immunology Exam 2 Questions And Complete Solutions
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Course
PSU VBSC 211
Institution
PSU VBSC 211
How many specific B cell antigen receptors does a B cell make? - Correct Answer one
What poly peptide chains make up an antibody? What are these proteins
called? - Correct Answer 2 Light Chains
2 Heavy Chains
=4 Total
What are the parts of an antibody? - Correct Answer -Antigen Bind...
PSU VBSC 211: Immunology Exam 2 Questions And
Complete Solutions
How many specific B cell antigen receptors does a B cell make? - Correct Answer one
What poly peptide chains make up an antibody? What are these proteins
called? - Correct Answer 2 Light Chains
2 Heavy Chains
=4 Total
What are the parts of an antibody? - Correct Answer -Antigen Binding Region (2)
-Constant Region (Portion)
-2 Heavy Chain
-2 Light Chain
-Hinge(flexibility)
-Disulfide Bonds
Antigen Binding Region - Correct Answer - a region on an antibody that binds to antigens
-binds the epitope
-Composed of one constant and one variable domain of each of the heavy and the light chain
-Every immunoglobulin molecule has at least two of these sites
Constant Region (Portion) - Correct Answer determines the mechanism used to destroy antigen
Divided into 5 classes:
-IgM
, -IgG
-IgA
-IgD
-IgE
Heavy Chain - Correct Answer -made up of variable numbers of the Immunoglobulin domain
-made up of three gene segments:
*the V (variable),
*D (diversity)
*J (joining)
-encodes both the antigen binding region and the constant region
Hinge - Correct Answer allows for antibodies to be flexible
-that is relatively unstructured domain, which allows it great freedom of motion
Disulfide Bonds - Correct Answer -holds together the two halves of the antibody
-formed between two cysteine residues
What are the five isotypes of antibodies? How are they different from one
another? - Correct Answer IgA (alpha)
IgD (delta)
IgE (epsilon)
IgG (gamma)
IgM (mu)
They are classed according to the heavy chain
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