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NUR 339 ( LATEST 2024 / 2025 ) EXAM 20 | (ACTUAL EXAM ) QUESTIONS AND ANSWERS (SOLVED) $15.99   Add to cart

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NUR 339 ( LATEST 2024 / 2025 ) EXAM 20 | (ACTUAL EXAM ) QUESTIONS AND ANSWERS (SOLVED)

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NUR 339 ( LATEST 2024 / 2025 ) EXAM 20 | (ACTUAL EXAM ) QUESTIONS AND ANSWERS (SOLVED)

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  • October 23, 2024
  • 27
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • NUR 339 Ex
  • NUR 339 Ex
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NUR 339 Exam 20
1. Cell Cycle


G0 resting phase (becomes mitotically dormant)
2. Cell Cycle


G1 (Gap 1) cell prepares to make DNA

3. Cell Cycle


S Phase DNA synthesis actually takes place (most mutations occur during this phase)

4. Cell Cycle

G2 phase prepares for mitosis (cell division)

5. Cell Cycle

M phase mitosis

6. benign neoplasm


Composed of well-differentiated cells that resemble cells of tissues of origin

Slow growth rate
Remain localized to site of origin without capacity to infiltrate, invade, or metastasize May
become encapsulated
Less blood supply than malignant neoplasm
Usually do not cause death unless interfere with vital functions because of their location
Can cause alterations in body function thru abnormal alteration of hormones

7. Malignant Neoplasms


Atypical cell structure; abnormal nucleus & chromo- somes

,Lose differentiation or resemblance to origin cell--more anaplastic (lack cell differ- entiation)

Not cohesive, irregular growth pattern, no capsule formed, not distinct from sur- rounding tissue
Invade adjacent cells rather than pushing aside

Varying growth rates and do not die within normal timeframe More blood supply than normal

tissue (angiogenesis)


Hallmark Sign of malignancy


ability to metastasize or spread to distant sites

8. metastasis


Ability of CA cells to spread to distant sites

Clumps of malignant cells break off & travel thru blood (hematogenic spread) or lymph
(lymphatic spread) to new site - most are killed by body's defense mecha- nisms
In lymph nodes, CA may die, grow into mass, or remain dormant

9. Sentinel Node


initial lymph node to which primary tumor drains (used to deter- mine spread to lymph system)

10. Primary neoplasm

original tumor

11. Metastatic Site


secondary neoplasm (retains characteristics of primary tumor)




12. Growth Fraction

, ratio if dividing cells/ G0 cells

A tissue with a large percentage of proliferating cells and few cells in G0 has a high growth
fraction. Chemotherapeutic drugs are much more toxic to tissues that have a high growth
fraction than to tissues that have a low growth fraction.

13. Stage of cancer growth


Initiation


exposure of cells (especially those actively synthesizing DNA) to enough carcinogens that alter
cell's genome-irreversible mu- tation

14. Stage of cancer growth


Promotion


induction of unregulated accelerated growth by some agent, chemical, or endogenous hormone

15. Stage of cancer growth


Progression


tumor cells get malignant characteris- tics

16. Stage of cancer growth


proliferation


increase in the # of cancer cells

17. Stage of cancer growth

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