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AHN 577 - Final Test Study Guide

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AHN 577 - Final Test Study Guide Anemia - Ans:-Reduction in one or more major RBC measurements or RBC count Male: Hgb < 13.5 or Hct <41% Female: Hgb < 12 or Hct <36% Pernicious Anemia - Ans:-Caused by lack of intrinsic factors (IF) produced by parietal cells of the gastric mucosa; ...

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  • October 23, 2024
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  • 2024/2025
  • Exam (elaborations)
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GraceAmelia
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AHN 577 - Final Test Study Guide


Anemia - Ans:✔✔-Reduction in one or more major RBC measurements or RBC count


Male: Hgb < 13.5 or Hct <41%


Female: Hgb < 12 or Hct <36%


Pernicious Anemia - Ans:✔✔-Caused by lack of intrinsic factors (IF) produced by parietal cells of the

gastric mucosa; prevent Vit B12 absorption and causes Vit B12 deficiency


Vitamin B12 Deficiency Anemia - Ans:✔✔-Deficient in hydrochloric acid or pancreatic enzymes causing

inability to metabolize Vit B12


Folic Acid Deficiency Anemia - Ans:✔✔-↓RBCs and Hgb content caused by impaired production r/t ↓

serum folate


Anemia of Chronic Dz (ACD) - Ans:✔✔-1. Gradual onset anemia accompanied by:


• Chronic infection or inflammation


• Acute/Chronic immune activation (Rheumatoid arthritis)


• CKD &/or ESRD

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• Underlying malignancies


• ? Severe trauma, DM and advanced age




2. Reduction of RBC production by bone marrow d/t:


• Abnormal iron metabolism and reduced absorption from GI tract


• Inability to ↑ erythropoiesis in response to anemia


• Decreased in production of erythropoiesis


• Shortening of red cell life-span


Thalassemia - Ans:✔✔-Inherited disorder resulting in defective production of the globin portion of Hgb


Autoimmune disorder


Megaloblastic


Macrocytic


Normochromic - Ans:✔✔-Prenicious anemia indices


Megaloblastic & Macrocytic & normochromic - Ans:✔✔-Vit B12 Deficiency anemia




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Folic Acid Deficiency Anemia


Pernicious Anemia indices


Hypochromic & Microcytic - Ans:✔✔-Iron deficiency Anemia and Thalassemia indices


Normochromic & Normocytic sometimes Hypochromic & Mircrocytic - Ans:✔✔-Anemia of Chronic dz

(ACD)


Normochromic to hypochromic & Microcytic - Ans:✔✔-Thalassemia indices


Prevalence of Thalassemia - Ans:✔✔-Mediterranean, African, and Asian


Hgb - Ans:✔✔-Main component of RBC and the essential protein that combines w/ and transports O2 to

the body


Males: 13.5-18


Females: 12-16


Hct - Ans:✔✔-Measures % of volume of whole blood that is occupied by erythrocytes: the amount of

plasma to total RBC mass (RBC concentration)


Males: 40-54%


Females: 37-47%



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FIRST PUBLISH OCTOBER 2024




TIBC - Ans:✔✔-250-450


S. Iron - Ans:✔✔-50-150


MCV - Ans:✔✔-Average volume and size of individual erythrocytes.


MCV Levels - Ans:✔✔-Microcytic: <80


Normocytic: 80-100


Macrocytic: > 100


MCH - Ans:✔✔-Average amount and weight of Hgb contained in a single erythrocyte


26-34 pg


MCHC - Ans:✔✔-Average Hgb concentration or proportion of each RBC occupied by Hgb as a % (100 mL)


MCHC levels - Ans:✔✔-Hypochromic: < 32%


Normochromic: 32-36%


Hyperchromic: > 36%


Microcytic Disorders (MCV < 80) - Ans:✔✔-Iron deficiency anemia and Thalassemia




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