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NSG 533 Advanced Pharmacology EXAM 1 LATEST 2024.2025 EXAM ACCURATE FALL- SPRING (WILKES UNIVERSITY) GRADED A+ $15.49   Add to cart

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NSG 533 Advanced Pharmacology EXAM 1 LATEST 2024.2025 EXAM ACCURATE FALL- SPRING (WILKES UNIVERSITY) GRADED A+

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NSG 533 Advanced Pharmacology EXAM 1 LATEST 2024.2025 EXAM ACCURATE FALL- SPRING (WILKES UNIVERSITY) GRADED A+

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  • October 23, 2024
  • 56
  • 2024/2025
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NSG 533 - Advanced Pharmacology




NSG 533 Advanced Pharmacology EXAM 1 LATEST
2024.2025 EXAM ACCURATE FALL- SPRING (WILKES
UNIVERSITY) GRADED A+
What does a substrate for an enzyme mean?

It needs it to undergo metabolism




What is an enzyme inducer?

It increases clearance of the drug (decreased blood levels of drug--may need dose
increase)




What is an enzyme inhibitor?

It reduces clearance (increased blood levels of drug--may need dose decrease)




Who is at risk for drug toxicity?

Elderly, those with decreased renal function



-Cannot properly excrete the drug

,NSG 533 - Advanced Pharmacology




What are the key pharmacokinetic changes that occur during pregnancy?

-Decreased absorption

-Increased hepatic metabolism

-Increased renal excretion



**Dose adjustments are common during pregnancy




What is the safest drug category for pregnant women?

Category A




What is the contraindicated drug category for pregnant women?

Category X




What is pharmacodynamics?

What the drug does to the body

,NSG 533 - Advanced Pharmacology


What is a drug's half-life?

The time it takes for the concentration of a drug in the body to be reduced by
50%




How many half-lives does it take to remove most of the drug from the body?

Appx 4




Why is knowing half-life important?

When switching to another drug that cannot be given with the previous drug.




How to determine when drug will be cleared from body:

Multiply half-life of drug by 4



Ex: Half-life of drug A = 8 hours



8 x 4 = 32 hours (how long you'd need to wait before starting the contraindicated
new drug B)

, NSG 533 - Advanced Pharmacology


What is therapeutic index?

Statement of the relative safety of a drug




Which is safer: a wide TI or a narrow TI?

A wide TI is safer (more dosing options before reaching toxic effects)




What is the minimum effective concentration?

The minimum amount of drug required to produce a therapeutic effect




What is receptor desensitization?

Decreased responsiveness of the receptor to the drug; decreased overall effects




How does antibiotic resistance occur?

The bacteria find a way to become resistant to the antibiotic. They multiply
leading to an ineffective antibiotic




How to prevent antibiotic resistance:

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