Neuropharmacology - Advanced Pharm - NURS8024 - Exam Three Questions And Complete Solutions
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Course
Neuropharmacology - Advanced Pharm - NURS80
Institution
Neuropharmacology - Advanced Pharm - NURS80
In Parkinson's disease the amount of __________ lost directly correlates to severity of symptoms. - Correct Answer Dopamine
The goal of treatment for Parkinson's disease is to CURE and REVERSE degeneration. T / F - Correct Answer False - Tx focus is on restoring balance
Sinamet (Levodopa ...
Neuropharmacology - Advanced Pharm - NURS8024 -
Exam Three Questions And Complete Solutions
In Parkinson's disease the amount of __________ lost directly correlates to severity of
symptoms. - Correct Answer Dopamine
The goal of treatment for Parkinson's disease is to CURE and REVERSE degeneration.
T / F - Correct Answer False - Tx focus is on restoring balance
Sinamet (Levodopa & Carbidopa) MOA includes: - Correct Answer Assist in
conversion of levodopa to dopamine in the basal nigra - Increase in body's production of
dopamine
How does Carbidopa help in Parkinson's disease? - Correct Answer Carbidopa
enhances availability of levodopa to cross the BBB. Decrease metabolism of levodopa
in the GI system
An NP understand that treatment effectiveness _____________ between the 3rd and
5th year of Parkinson treatment using sinemet. - Correct Answer Decreases
Important Pt Ed on Levodopa: - Correct Answer Take on an Empty Stomach
ADE with Levodopa include: - Correct Answer CNS effects (Visual/Auditory
Hallucinations, AIM, depression, GI effects, Tachy, Acute glaucoma
Amantadine is used to treat? - Correct Answer MINOR Parkinsons
Use MAO-B Inhibitors _____________ and adjunct with __________. - Correct Answer
Early ; Levodopa
COMT (Catehcol-O-Methyltransferase Inhibitors) - Correct Answer Help with uptake of
Levodopa which increases dopamine in CNS
CAUTION when using _______________ & ___________ as both are major enzymes
that metabolize catecholamines. - Correct Answer MAO-B and COMT
Anticholinergics in Parkinson's disease are prescribed because........ - Correct Answer
Decrease Tremors
Decrease Rigidity
Decrease Drooling
An experienced NP would know what about medication to treat Alzheimers disease? -
Correct Answer Drugs are palliative - Provides only modest ST benefits - FATAL
Name the three types of Alzheimers Disease: - Correct Answer Accumulation of Senile
Plaques (Beta-Amyloid)
Formation of numerous neurofibrillary tangles
Loss of Cortical Neurons - Especially Cholinergic neurons
After PCP consult which medication can be started for EARLY Alzheimers Disease? -
Correct Answer Donepezil (Aricept or EARLYCEPT), Rivastigmine (Exelon),
Galantamine (Razadyne)
Which Alzheimers Medication would an NP start later in the disease? - Correct Answer
NamENDa
What is the MOA of NamENDa? - Correct Answer Blocks enzymes that destroy
acetylcholine
What important ADE would the NP educate the patient on with NamENDa? - Correct
Answer GI, Insominia, Fatigue, Muscle Cramping, Anorexia
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