Narrow spectrum antibiotics - Correct Answer Act on single or limited group of
microorganisms
Known pathogen
Ideal
Extended spectrum antibiotics - Correct Answer Efficacy against large numbers of
gram positive or gram negative organisms
Broad Spectrum (empiric therapy) - Correct Answer Effective against broad spectrum
Unknown pathogen, but possibly life threatening
Risk for superinfections
Superinfections - Correct Answer Use of broad spectrum agents can disrupt the
normal flora causing growth of opportunistic organisms (PCN causing vag yeast)
, Empiric regimen - Correct Answer Imitated before the offending organism identified
and sometimes prior to confirmation of infection
Definitive regimen - Correct Answer Initiated when causative organism is known
Minimum inhibitory concentration (MIC) - Correct Answer Estimate of the drug
sensitivity of pathogens for comparison with anticipated levels in blood or tissues
Post-antibiotic effect (PAE) - Correct Answer AB effect that persists after drug
concentration falls below the MIC
Susceptibility testing - Correct Answer Laboratory methods to determine to the
sensitivity of the isolated pathogen to anti microbial drugs
Bacteriostatic antomicrobial - Correct Answer Inhibits growth and replication of
bacteria
Limits spread of infection
Enables immune system to attack pathogen
Bacterialcidal antimicrobial - Correct Answer Kills bacteria
Total number of viable organisms decreases
Concentration-dependent killing - Correct Answer Increased rate of killing with
increased concentration
Usually offers a daily dose to achieve efficacy
Aminoglycosides & quinolones
Time-dependent killing - Correct Answer bactericidal activity dependent on time serum
concentration
Protein synthesis inhibitors - Correct Answer tetracyclines, aminoglycosides,
macrolides
Inhibitors of nucleic acid function or synthesis - Correct Answer Fluoroquinolones
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller Victoria108. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $11.49. You're not tied to anything after your purchase.