Gender: females are 2-3x more likely than men to get it
-European-Americans are more likely than other groups - ANSWER Risk factors for
rheumatoid arthritis:
-Chronic (longer than 6 months)
-Inflammatory (increased WBC)
-Progressive (gets worse)
-Systemic (effecting whole body) - ANSWER What is rheumatoid arthritis?
Synovium - ANSWER Transformed autoantibodies (rheumatoid factors) attack healthy
tissue of the _____, causing inflammation.
Rheumatoid arthritis - ANSWER Articulate cartilage, joint capsule, ligaments and
tendons become involved in this disease, cartilage breaks down and fluid accumulated
in the joint space
Pannus - ANSWER ___ forms in rheumatoid arthritis which is vascular granulation tissue
made of inflammatory cells that erodes cartilage and can destroy bone
Pannus - ANSWER ____ breaks down cartilage and bone
Mobility
Pain
Immunity - ANSWER Which concepts are involved in rheumatoid arthritis:
-early morning stiffness
, -joint inflammation
-low grade fever
- 2-3 pound weight loss
-fatigue
-weakness
-often joints of upper extremities involved (hand/wrist) - ANSWER Early symptoms of
RA?
-Joint deformities
-Moderate/severe pain (exacerbation/remission)
-osteoporosis
-anemia
-weight loss (more severe)
-Subcutaneous nodules
-Peripheral neuropathy (usually starts in toes and fingers, usually toes and can travel
up)
-Vasculitis/pericarditis/myocarditis - ANSWER Late symptoms of RA?
Early morning - ANSWER RA is characterized by ____ ____ stiffness but gets better as
they start walking within 30 min usually
Osteoarthritis - ANSWER Bouchard deformity is found in _____
Boutonniere deformity(of thumb usually), ulnar deviation of metacarpophalangeal joints
(fingers swayed to side of ulna), swan-neck deformity - ANSWER Types of RA
deformities:
X-ray/CT scan: looking for joint changes, deformities, fluid in joint
CBC: looking for an increase in WBCs
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