response when activated: inhibition of norepinephrine release,
vasoconstriction
ACE inhibitors Correct Answer Antihypertensive. Blocks ACE
in lungs from converting angiotensin I to angiotensin II
(powerful vasoconstrictor). Decreases BP, Decreased
Aldosterone secretions, Sodium and fluid loss.
Check BP before giving (hypotension)
*Orthostatic Hypotension
-"PRIL" LISINOPRIL
acute arterial ischemic disorders Correct Answer sudden
interruption in arterial blood supply to a tissue, organ, or
extremity
-often called insulin shock, insulin reaction, or the lows
-mismatch between insulin intake, physical activity, and
carbohydrate availability (error in insulin dose, missing a meal,
intake of alcohol, certain medications)
-severe conditions may cause death
acute leukemia Correct Answer presence of undifferentiated or
immature cells, usually blast cells
prognosis: 5 year survival 80% for children but 40% for adults
bond/abdominal, CNS pain
chemo: corticosteroids and vinca alkaloids
bone marrow transplant
Acute Myelogenous Leukemia (AML) Correct Answer rapidly
progressive neoplasm of cells committed to the myeloid line of
development
all age groups impacted >60 y.o.
, prognosis highly variable- the younger the patient the better the
prognosis
"undifferentiated" form: worse prognosis
neutropenia: fever, weakness, bleeding
chemo: aggressive induction therapy
bone marrow transplant
Adrenergic inhibiting agents Correct Answer act by
diminishing the SNS effects that increase BP. Adrenergic
inhibitors include drugs that act centrally on the vasomotor
center and peripherally to inhibit norepinephrine release or to
block the adrenergic receptors on blood vessels.
-PRAZOSIN
African Americans and HTN Correct Answer -highest
prevelence; more resistant HTN, develop at younger age; female
greater than male; more nocturnal nondipping BP; more end-
organ damage, highest death rate
-less response to renin inhibiting meds; better control with
calcium channel blockers and diuretics
-increased risk for angioedema with ACE inhibitors
albumin Correct Answer protein in blood; maintains the proper
amount of water in the blood
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