WARM AUTOIMMUNE HEMOLYTIC ANEMIAS –
SBB QUESTIONS AND ANSWERS VERIFIED BY
EXPERT | LATEST UPDATE 2025
What are primary and secondary causes of Warm Auto Immune Hemolytic
anemia? - ANSWER Primary: Idiopathic / Secondary: Chronic Lymphocytic
Leukemia, Systemic Lupus for WAIHA
What temperature do Warm Autoimmune Hemolytic antibodies react at? -
ANSWER 37 degrees Celsius for WAIHA
What immunglobulin class are WAIHA antibodies? - ANSWER IgG for WAIHA
What percentage of AutoImmune Hemolytic Anemias do WAIHAs make up? -
ANSWER WAIHA: 48-70% of all AIHA
What are the Direct Antiglobulin Testing results most often seen with WAIHA? -
ANSWER "WAIHA DAT: IgG + C3 = 67%, IgG = 20%,C3 = 13%"
When are elutions performed? - ANSWER Elutions are performed when an IgG
Antibody is identified during a direct antiglobulin test for WAIHA
WAIHA antibodies are specific for what antigens? - ANSWER Rh and little e
(usually none) for WAIHA
What is meant by "Least Incompatible?" - ANSWER Same as "Most
Compatible" using multiple techniques like Warm autoadsorption, Allogeneic
adsorption, or Phenotypically matched blood
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