MCB10 FinalMCB10 Final Exam Study Guide- Test Questions With Answers Exam Study Guide- Test Questions With Answers
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MCB10
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MCB10
MCB10 Final Exam Study Guide- Test Questions With Answers
CQ-If a cell loses the function of both alleles of a tumor suppressor gene, what do you think would happen? - Answer-increased cell division
/.CQ- Phenotypes of human behavior such as autism, addiction, or eating disorders are..(_____...
MCB10 Final Exam Study Guide- Test
Questions With Answers
CQ-If a cell loses the function of both alleles of a tumor suppressor gene, what do you
think would happen? - Answer-increased cell division
/.CQ- Phenotypes of human behavior such as autism, addiction, or eating disorders
are..(______ traits) - Answer-multifactorial traits
/.CQ- Clinical depression can be treated with antidepressant drugs like Prozac, Paxil or
Zoloft. How do they work? - Answer-Decreasing the uptake of serotonin into the
presynaptic neuron
/.CQ- Which of the following would you predict to lead to a genetic predisposition to
"thrill seeking" behavior? - Answer--environmental factors in the womb leading to
increased DNA methylation of the gene encoding the D4 dopamine receptor in the
developing fetus
-an individual that is heterozygous for a nonsense mutation in the gene encoding the D2
dopamine receptor protein
/.CQ-What would happen if the cell cycle proceeded normally, except that physical
division of the cell did not occur? - Answer-a large cell with multiple nuclei would result
/.CQ- Rb is a tumor suppressor gene that when non-functional leads to retinoblastoma,
a cancer of the eye. You are volunteering at a clinic where they diagnose and treat
children with retinoblastoma. If you see a patient who has retinoblastoma in BOTH
EYES it is most likely that the child... - Answer-inherited a mutant allele of Rb, and
acquired mutations in the other allele of Rb in both eyes
/.CQ- What is the normal Her2 Gene? - Answer-a proto-oncogene
/.CQ-Which is the best description of what Herceptin is? - Answer-an inhibitor of an
oncogene
/.CQ-In a sample from a given population, the following genotypes were observed for
the gene ALPHA
60A/A ; 130 A/a ; 40 a/a
What is the allele frequency of a? - Answer-0.46
/.CQ- Cystic fibrosis is a recessive condition. The incidence of people who have Cystic
Fibrosis in the population is 1/20000=0.0005. What is the predicted frequency of Cystic
Fibrosis carriers in the population? - Answer-0.043
, /.CQ- Which of the following would NOT increase genetic diversity within a population? -
Answer-population bottle neck
/.CQ- In 1600s a shipwrecked slave ship land on the island of St. Vincent in the
Caribbean. Many of the enslaved West African individuals aboard the ship survived and
joined a native island with another populations forming a new ethnic group. they
resulted from...( migration, bottle neck, mutation, founder effect) - Answer-migration
/.CQ- what was the mechanism of evolution that caused the lactase persistence alleles
of the LCT gene to increase in cattle-herding population over many generations? -
Answer-Natural selection of a heritable germline mutation that enables an individual to
digest milk
/.CQ-Whole genome sequencing can be used to - Answer--identify disease causing
genetic mutations
-identify variations in the genome that increase a persons risk for disease
-identify specific mutations in a malignant cancer and lead to a personalized treatment
/.CQ- the GATA repeated sequence shown is a - Answer-STR
/.CQ-A missense mutation results for a single base change in exon 4 of the hemoglobin
gene. This single base change is found in 1.6% of the population. Many individuals with
this variant have sick-cell anemia.How would you classify this variant? - Answer-A
causative coding SNP
/.CQ- An individual with two different STR alleles, one of 15 repeats and the other of 18
repeats, mates with and individual who has two copies of the 18 repeat allele at this
STR. What are the possible genotypes of their child with regard to this STR? - Answer--
15,18
-18,18
/.PS1- A Human somatic cell has just completed mitosis, resulting in two daughter cells.
How many copies of the DBA2 gene does each daughter cell have? (assume the
daughter cells are in G1 of the cell cycle) - Answer-2 copies
/.PS1-Another human somatic cell has just completed S phase of the cell cycle, how
many copies of the DBA2 gene does the cell have? (assume the cell is in prophase of
mitosis) - Answer-4 copies
/.PS1-Diamond-Blackfan anemia is a dominant phenotype. What is the genotype of an
individual that has Diamond-Blackfan Anemia? - Answer-Heterozygous for the DBA2
mutant allele.
/.PS1- Two people, both of whom do not have Diamond-Blackfan Anemia, mate and are
expecting a child. What is the most likely probability that this child will have Diamond-
Blackfan Anemia? - Answer-0 chance
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